Biomaterial delivery device, and related systems and methods

Patent metadata

Field	Value
Publication number	US-11298242-B2
Application number	US-201916441951-A
Country	US
Kind code	B2
Filing date	Jun 14, 2019
Priority date	Jun 14, 2019
Publication date	Apr 12, 2022
Grant date	Apr 12, 2022

Abstract

A system for delivering flowable biomaterial to an intervertebral disc space between adjacent vertebral bodies includes a delivery body defining a proximal end, a distal end spaced from the proximal end along a longitudinal direction, a cannulation extending from the proximal end to an opening adjacent the distal end, and a distal region including a tip that extends to the distal end. The distal region defines a maximum height at a location proximal of the distal end and measured along a second direction perpendicular to the longitudinal direction. The distal region is for indicating a distance between the adjacent vertebral bodies. The system includes a carrier having a longitudinaly elongate channel for carrying biomaterial and being insertable within the cannulation, as well as an advancement member configured for insertion within the cannulation to forcibly advance the biomaterial from the cannulation, through the opening, and into the disc space.

First claim

What is claimed:

1. A system for delivering flowable biomaterial into an intervertebral disc space between an upper vertebral body and a lower vertebral body of a patient, the system comprising:
a plurality of delivery bodies each configured for delivering the biomaterial, each of the plurality of delivery bodies defining:
a proximal end, an elongate outer surface extending from the proximal end to a distal end spaced from the proximal end along a longitudinal direction, a mounting formation at the proximal end, the mounting formation configured to couple with a handle member, a cannulation opposite the outer surface along a radial direction, the cannulation extending from the proximal end to at least one opening adjacent the distal end;
a distal region including a tip that extends to the distal end, the distal region defining a maximum height at a location proximally spaced from the distal end, the maximum height measured along a second direction perpendicular to the longitudinal direction,
wherein the maximum heights of at least some of the distal regions of the plurality of delivery bodies are different from one another, and the distal regions are configured to provide feedback indicating a distance between the upper and lower vertebral bodies along a cranial-caudal direction;

a carrier that defines a channel elongate along the longitudinal direction, the carrier configured for insertion within the cannulation from the proximal end of any of the plurality of delivery bodies to carry the biomaterial within the cannulation; and
an advancement member configured for insertion within the cannulation of any of the plurality of delivery bodies so as to forcibly advance the biomaterial from the cannulation, through the at least one opening, and into the interverbal disc space.

2. The system of claim 1 , wherein the distal region defines a first contact surface and a second contact surface opposite each other along the second direction, the maximum height is defined between the first and second contact surfaces, and the first and second contact surfaces are configured to contact opposed endplates of the first and second vertebral bodies, respectively.

3. The system of claim 2 , wherein the first and second contact surfaces each have a substantially linear profile in a reference plane orthogonal to a central axis of the respective delivery body.

4. The system of claim 2 , wherein the tip defines tapered surfaces extending from the location to the distal end, and the tapered surfaces are configured to expand the distance between the first and second vertebral bodies along the cranial-caudal direction as the delivery body advances distally into the intervertebral disc space.

5. The system of claim 1 , wherein the at least one opening includes a pair of opposed side openings spaced from each other along a third direction perpendicular to the longitudinal and second directions.

6. The system of claim 5 , wherein at least one of the delivery bodies includes a wedge formation at a distal terminal end of the cannulation, and the wedge formation faces proximally and intersects a central axis of the cannulation, whereby the wedge formation is configured to divert the biomaterial from the cannulation out the pair of opposed side openings.

7. The system of claim 5 , wherein the at least one opening includes a third opening at the distal end, wherein a central axis of the at least one of the delivery bodies extends through the third opening.

8. The system of claim 1 , wherein the at least one opening is a single opening that is open at least along a third direction perpendicular to the longitudinal and second directions.

9. The system of claim 1 , wherein the at least one opening of at least one of the plurality of delivery bodies is located at the distal end such that a central axis of the at least one of the delivery bodies extends through the at least one opening.

10. A system for delivering flowable biomaterial into an intervertebral disc space between an upper vertebral body and a lower vertebral body of a patient, the system comprising:
a plurality of delivery bodies each configured for delivering the biomaterial, each of the plurality of delivery bodies defining:
a proximal end, a distal end spaced from the proximal end along a longitudinal direction, a cannulation extending from the proximal end to at least one opening adjacent the distal end,
a distal region including a tip that extends to the distal end, the distal region defining a maximum height at a location proximally spaced from the distal end, the maximum height measured along a second direction perpendicular to the longitudinal direction,
wherein the maximum heights of at least some of the distal regions of the plurality of delivery bodies are different from one another, and the distal regions are configured to provide feedback indicating a distance between the upper and lower vertebral bodies along a cranial-caudal direction;

a carrier that defines a channel elongate along the longitudinal direction, the carrier configured for insertion within the cannulation of any of the plurality of delivery bodies to carry the biomaterial within the cannulation; and
an advancement member configured for insertion within the cannulation of any of the plurality of delivery bodies so as to forcibly advance the biomaterial from the cannulation, through the at least one opening, and into the interverbal disc space,
wherein:
the at least one opening of at least one of the plurality of delivery bodies is located at the distal end such that a central axis of the at least one of the delivery bodies extends through the at least one opening,
at least one of the plurality of delivery bodies defines an interior surface that defines the cannulation, the interior surface defines helical threads extending along a distal portion of the cannulation that extends to the distal end,
the advancement member defines a complimentary distal member portion that defines a pair of opposed surfaces that are substantially planar and spaced from each other along a direction perpendicular to a central axis of the at least one of the plurality of delivery bodies, and
the at least one of the plurality of delivery bodies is rotatably connectable to the advancement member about the central axis, whereby the at least one delivery body and the advancement member are cooperatively configured such that rotation of the helical threads relative to the pair of opposed surfaces about the central axis advances the biomaterial distally through the cannulation and out the at least one opening and into the intervertebral disc space.

Assignees

• Medos Int Sarl

Inventors

• Murray James
• Hawkins John Riley
• Cleveland Benjamin
• Mcdermott Alicia
• Lomeli Roman
• Dieselman John
• Bornhoft Stephen
• Ramsay Christopher
• Pavento Nicholas
• Klett Jan
• Gully Stephane
• Buehlmann Eric
• Gamache Thomas
• Berger Roger

Classifications

• A61F2002/2835

  Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material · CPC title

• A61B17/8819

  characterised by the introducer proximal part, e.g. cannula handle, or by parts which are inserted inside each other, e.g. stylet and cannula (A61B17/8825 takes precedence) · CPC title

• A61B17/8822

  characterised by means facilitating expulsion of fluid from the introducer, e.g. a screw pump plunger, hydraulic force transmissions, application of vibrations or a vacuum · CPC title

• A61F2/4657

  Measuring instruments used for implanting artificial joints (for surgical instruments A61B90/06) · CPC title

• A61F2/4601 Primary

  for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity · CPC title