Methods of detection and removal of rhabdoviruses from cell lines
US-10501500-B2 · Dec 10, 2019 · US
Methods of detection and removal of rhabdoviruses from cell lines
US11286282B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11286282-B2 |
| Application number | US-201916662784-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 24, 2019 |
| Priority date | Oct 3, 2013 |
| Publication date | Mar 29, 2022 |
| Grant date | Mar 29, 2022 |
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- Title
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- Abstract
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Abstract
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The present disclosure relates to compositions, methods, mixtures, and kits for detecting the presence of, and for removing, a virus from a product produced in an insect cell. The disclosure also relates to proteins, peptides, polypeptides, drug substances, biological products, vaccine antigens, and virus-like particles that are produced in an insect cell and that are free or substantially free of a virus. The disclosure also relates to compositions, methods, assays, and kits for detecting a rhabdovirus in a sample.
First claim
Opening claim text (preview).
What is claimed is: 1. A rhabdovirus-free Sf9 or Sf21 insect cell comprising a biological product. 2. The insect cell of claim 1 , wherein the insect cell is free of a nucleotide sequence having at least 70% homology to SEQ ID NO:1. 3. The insect cell of claim 1 , wherein the insect cell is an Sf9 cell. 4. The insect cell of claim 3 , wherein the Sf9 cell is derived from the cell line deposited as ATCC CRL-1711. 5. The insect cell of claim 1 , wherein the biological product is a protein, peptide, drug substance, virus-like particle (VLP), DNA, RNA, virus, or vaccine antigen. 6. The insect cell of claim 1 , wherein the biological product is a recombinant virus for gene therapy. 7. The insect cell of claim 1 , wherein the biological product is a protein or virus-like particle (VLP). 8. The insect cell of claim 1 , wherein the insect cell is free of a nucleotide sequence comprising the sequence according to SEQ ID NO: 1.
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Inventors
Classifications
Extraction; Separation; Purification · CPC title
- C12Q1/701Primary
Specific hybridization probes · CPC title
- C12N7/00Primary
Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof (preparing medicinal viral antigen or antibody compositions, e.g. virus vaccines, A61K39/00) · CPC title
Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein · CPC title
Methods of production or purification of viral material · CPC title
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Frequently asked questions
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- What does patent US11286282B2 cover?
- The present disclosure relates to compositions, methods, mixtures, and kits for detecting the presence of, and for removing, a virus from a product produced in an insect cell. The disclosure also relates to proteins, peptides, polypeptides, drug substances, biological products, vaccine antigens, and virus-like particles that are produced in an insect cell and that are free or substantially free…
- Who is the assignee on this patent?
- Takeda Vaccines Inc
- What technology area does this patent fall under?
- Primary CPC classification C12Q1/701. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 29 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).