Bioimplant with evanescent coating film

Patent metadata

Field	Value
Publication number	US-11278642-B2
Application number	US-202016823175-A
Country	US
Kind code	B2
Filing date	Mar 18, 2020
Priority date	Sep 8, 2006
Publication date	Mar 22, 2022
Grant date	Mar 22, 2022

Abstract

To provide a bioimplant capable of controlling a rate of an antibacterial agent and an antibiotic to be eluted from the coating film. An evanescent coating film made of a calcium phosphate-based material having crystallinity of 10% to 90% is formed at a predetermined area of the bioimplant and an antibacterial agent or an antibiotic is contained in the coating film to suppress adhesion of bacteria.

First claim

What is claimed is:

1. A bioimplant, comprising:
an implant comprising a stem portion and a neck portion; and
an evanescent coating film comprising a calcium phosphate-based material formed on a first surface of the stem portion by thermal spraying,
wherein the evanescent coating film comprises a silver material distributed in the evanescent coating film, has a thickness in the range of 5 micrometers to 100 micrometers, and has a crystallinity in the range of 10% to 90% and
wherein an evanescence period of the evanescent coating film is configured to be a predetermined period in the range of 6 weeks to 120 months by selecting a combination of the thickness and the crystallinity of the evanescent coating film.

2. The bioimplant of claim 1 , wherein the evanescent coating film is not disposed on a surface of the neck portion.

3. The bioimplant of claim 2 , wherein the evanescent coating film does not cover a second surface of the stem portion, wherein the first and second surfaces laterally surround a portion of the stem.

4. The bioimplant of claim 1 , wherein the calcium phosphate-based material has a crystallinity of 60% to 90%.

5. The bioimplant of claim 1 , wherein a thickness of the evanescent coating film is in the range of 50 to 100 micrometers (μm).

6. The bioimplant of claim 1 , wherein the thickness of the evanescent coating film is in the range of 20 and 40 micrometers (μm).

7. The bioimplant of claim 1 , wherein an elution period of the silver material when the implant is placed in a body fluid is at least six months.

8. A bioimplant, comprising:
an implant comprising a metal or metal alloy material; and
an evanescent coating film comprising a calcium phosphate-based material formed on a first surface of the implant by thermal spraying,
wherein the evanescent coating film comprises silver metal particles distributed in the evanescent coating film, has a crystallinity in the range of 10% to 90%, and has a thickness in the range of 5 to 100 micrometers (μm), and
wherein an evanescence period of the evanescent coating film is configured to be a predetermined period in the range of 6 weeks to 120 months by selecting a combination of the thickness and the crystallinity of the evanescent coating film.

9. The bioimplant of claim 8 , wherein the thickness of the evanescent coating film is in the range of 20 and 40 micrometers (μm).

10. The bioimplant of claim 8 , wherein the implant comprises a stem portion and a neck portion, and the evanescent coating film is not disposed on a surface of the neck portion.

11. The bioimplant of claim 10 , wherein the implant comprises a stem portion and a neck portion, and the evanescent coating film does not cover a second surface of the stem portion, wherein the first and second surfaces laterally surround a portion of the stem.

12. The bioimplant of claim 8 , wherein the calcium phosphate-based material has a crystallinity of 60% to 90%.

13. The bioimplant of claim 8 , wherein an elution period of the silver metal particles when the implant is placed in a body fluid is at least six months.

14. A bioimplant, comprising:
an implant comprising a stem portion and a neck portion;
an evanescent coating film comprising a calcium phosphate-based material and a silver material formed on a first surface of the stem portion by thermal spraying; and
a shell configured to receive the neck portion therein, the shell comprising an upper hemispherical surface,
wherein the evanescent coating film covers the upper hemispherical surface,
wherein the calcium phosphate-based material has a crystallinity of 10% to 90%,
wherein the evanescent coating film has a thickness in the range of 5 and 100 micrometers (μm), and
wherein an evanescence period of the evanescent coating film is configured to be a predetermined period in the range of 6 weeks to 120 months by selecting a combination of the thickness and the crystallinity of the evanescent coating film.

15. The bioimplant of claim 14 , wherein the evanescent coating film is not disposed on a surface of the neck portion.

16. The bioimplant of claim 15 , wherein the evanescent coating film does not cover a second surface of the stem portion, wherein the first and second surfaces laterally surround a portion of the stem.

17. The bioimplant of claim 14 , wherein the thickness of the evanescent coating film is in the range of 20 and 40 micrometers (μm).

18. The bioimplant of claim 14 , wherein the calcium phosphate-based material has a crystallinity of 60% to 90%.

Assignees

• Kyocera Corp
• Hotokebuchi Takao
• Takao Hotokebuchi

Inventors

• Hotokebuchi Takao
• Noda Iwao

Classifications

• A61L2430/02

  for reconstruction of bones; weight-bearing implants · CPC title

• A61L2300/404

  Biocides, antimicrobial agents, antiseptic agents · CPC title

• A61L27/32 Primary

  Phosphorus-containing materials, e.g. apatite · CPC title

• A61L2420/04

  Coatings containing a composite material such as inorganic/organic, i.e. material comprising different phases · CPC title

• A61L27/06

  Titanium or titanium alloys · CPC title