Systems and methods for onsite sorbent material reuse

Patent metadata

Field	Value
Publication number	US-11253849-B2
Application number	US-201816203119-A
Country	US
Kind code	B2
Filing date	Nov 28, 2018
Priority date	Nov 28, 2018
Publication date	Feb 22, 2022
Grant date	Feb 22, 2022

Abstract

Methods, sorbent cartridges and cleaning devices are disclosed for refurbishing sorbent materials. In one implementation among multiple implementations, a medical fluid delivery method includes: providing a sorbent cartridge including H+ZP within a casing for a treatment; and after the treatment, refurbishing the H+ZP while maintained within the casing via (i) regenerating the non-disinfected H+ZP by flowing an acid solution through the casing, (ii) rinsing the regenerated H+ZP while maintained within the casing, (iii) disinfecting the regenerated and rinsed H+ZP by flowing a disinfecting agent through the casing, and (iv) rinsing the regenerated and disinfected H+ZP while maintained within the casing. Multiple batch sorbent refurbishing implementations are also disclosed.

First claim

The invention claimed is:

1. A medical fluid delivery method comprising:
providing a sorbent cartridge including H + ZP within a casing for a treatment; and
after the treatment, refurbishing the H + ZP while maintained within the casing via
regenerating the non-disinfected H + ZP by flowing an acid solution through the casing,
rinsing the regenerated H + ZP while maintained within the casing,
disinfecting the regenerated and rinsed H + ZP by flowing a disinfecting agent through the casing, and
rinsing the regenerated and disinfected H + ZP while maintained within the casing,

wherein the casing including the refurbished H + ZP is replaced within the sorbent cartridge along with at least one new and different type of casing.

2. The medical fluid delivery method of claim 1 , wherein at least one of the rinsing procedures includes rinsing the H + ZP with water through the casing until a desired conductivity is reached.

3. The medical fluid delivery method of claim 1 , wherein the first rinsing procedure includes rinsing the H + ZP with water through the casing in a reverse-to-treatment flow direction and the second rinsing procedure includes rinsing the H + ZP with water through the casing in a normal treatment flow direction.

4. The medical fluid delivery method of claim 1 , wherein disinfecting the rinsed and regenerated H + ZP includes flowing the disinfecting agent through the casing in a reverse-to-treatment flow direction.

5. The medical fluid delivery method of claim 1 , wherein regenerating the non-disinfected H + ZP includes flowing the acid solution through the casing in a reverse-to-treatment flow direction.

6. The medical fluid delivery method of claim 1 , wherein regenerating the non-disinfected H + ZP includes at least one of flowing the acid solution through the casing (i) at a flowrate of 0.1 ml/min to 5 ml/min, (ii) at a temperature from about 20° C. to about 80° C., or (iii) until eluent acid used to contact the H + ZP has a pH that equals or substantially equals a pH of incoming acid solution.

7. The medical fluid delivery method of claim 1 , wherein at least one of (a) the acid solution is HCl, H 2 SO 4 , H 3 PO 4 , HNO 3 or acetic acid or (b) the disinfecting agent (i) is a hydrogen based chemical, such as including HOCl or (ii) includes isopropyl alcohol (“IPA”).

8. A medical fluid delivery method comprising:
providing a sorbent cartridge including Na + ZP within a casing for a treatment; and
after the treatment,
refurbishing the Na + ZP while maintained within the casing via regenerating the non-disinfected Na + ZP using by flowing a sodium based alkaline solution or a sodium salt solution through the casing,
rinsing the regenerated Na + ZP while maintained within the casing,
disinfecting the regenerated and rinsed Na + ZP by flowing a disinfecting agent through the casing, and
rinsing the regenerated and disinfected Na + ZP while maintained within the casing,

wherein the casing including the refurbished Na + ZP is replaced within the sorbent cartridge along with at least one new and different type of casing.

9. The medical fluid delivery method of claim 8 , wherein at least one of the rinsing procedures includes rinsing the Na + ZP with water through the casing until a desired conductivity is reached.

10. The medical fluid delivery method of claim 8 , wherein the first rinsing procedure includes rinsing the Na + ZP with water through the casing in a reverse-to-treatment flow direction and the second rinsing procedure includes rinsing the Na + ZP with water through the casing in a normal treatment flow direction.

11. The medical fluid delivery method of claim 8 , wherein disinfecting the rinsed and regenerated Na + ZP includes flowing the disinfecting agent through the casing in a reverse-to-treatment flow direction.

12. The medical fluid delivery method of claim 8 , wherein regenerating the non-disinfected Na + ZP includes flowing the sodium based alkaline solution or the sodium salt solution through the casing in a reverse-to-treatment flow direction.

13. The medical fluid delivery method of claim 8 , wherein regenerating the non-disinfected Na + ZP includes at least one of flowing the sodium based alkaline solution or the sodium salt solution through the casing (i) at a flowrate of 0.1 ml/min to 5 ml/min, (ii) at a temperature from about 20° C. to about 80° C., or (iii) until eluent sodium solution used to contact the Na + ZP has a conductivity that equals or substantially equals a conductivity of incoming sodium solution.

14. The medical fluid delivery method of claim 8 , wherein the disinfecting agent (i) is a sodium based chemical, such as including NaOCl or (ii) includes isopropyl alcohol (“IPA”).

15. A medical fluid delivery method comprising:
providing a sorbent cartridge including Na + ZP within a casing for a treatment; and
after the treatment, refurbishing the Na + ZP while maintained within the casing via
disinfecting the non-regenerated Na + ZP by flowing a disinfecting agent through the casing,
rinsing the disinfected Na + ZP while maintained within the casing,
regenerating the disinfected and rinsed Na + ZP by flowing a sodium based alkaline solution or a sodium salt solution through the casing, and
rinsing the disinfected and regenerated Na + ZP while maintained within the casing,

wherein the casing including the refurbished Na + ZP is replaced within the sorbent cartridge along with at least one new and different type of casing.

16. The medical fluid delivery method of claim 15 , wherein at least one of the rinsing procedures includes rinsing the Na + ZP with water through the casing until a desired conductivity is reached.

17. The medical fluid delivery method of claim 15 , wherein the second rinsing procedure includes rinsing the Na + ZP with water through the casing in a normal treatment flow direction.

18. The medical fluid delivery method of claim 15 , wherein regenerating the disinfected Na + ZP includes at least one of flowing the sodium based alkaline solution or the sodium salt solution through the casing (i) at a flowrate of 0.1 ml/min to 5 ml/min, (ii) at a temperature from about 20° C. to about 80° C., or (iii) until eluent sodium solution used to contact the Na + ZP has a conductivity that equals or substantially equals a conductivity of incoming sodium solution.

19. The medical fluid delivery method of claim 15 , wherein the disinfecting agent (i) is a sodium based chemical, such as including NaOCl or (ii) includes isopropyl alcohol (“IPA”).

Assignees

• Baxter Int
• Baxter Healthcare Sa

Inventors

• Ding Yuanpang Samuel
• Yeh Rosa Hung-Chen
• Bueno Cristian Adolfo Menzel
• Lao Ieng Kin

Classifications

• A61L2103/15

  Laboratory, medical or dentistry appliances, e.g. catheters or sharps · CPC title

• B01J20/28

  characterised by their form or physical properties · CPC title

• B01J20/02

  comprising inorganic material · CPC title

• A61M1/16 Primary

  with membranes · CPC title

• B01J20/3433

  of sorbents or filter aids other than those covered by B01J20/3408 - B01J20/3425 · CPC title