Implant coating

Patent metadata

Field	Value
Publication number	US-11241316-B2
Application number	US-202016830918-A
Country	US
Kind code	B2
Filing date	Mar 26, 2020
Priority date	Mar 29, 2019
Publication date	Feb 8, 2022
Grant date	Feb 8, 2022

Abstract

A medical implant structure is provided comprising a substrate 10 with at least a first surface and a second surface that surfaces differ from one another with regard to at least one property in relation to biological material.

First claim

The invention claimed is:

1. A medical implant structure comprising: a substrate with an interfacial layer to surrounding tissue formed by at least a first coating layer and a second coating layer, the first and second coating layers differing from one another with regard to at least one property in relation to biological material, wherein the substrate has an essentially porous and irregular surface, the substrate including recessed parts and most-protruding portions, wherein the first coating layer is a conformal coating that uniformly coats irregularities of the substrate, and wherein the second coating layer is a topmost, non-conformal coating deposited onto the most-protruding portions of said substrate surface, wherein said most-protruding portions of said substrate surface on which the second coating layer is deposited is void of said first coating layer, and wherein the second coating layer does not coat the recessed parts of the substrate.

2. The medical implant structure of claim 1 , in which the first coating layer and the second coating layer differ from one another in terms of at least one property selected from the group consisting of adhesion, cell growth, biological activity, and toxicity.

3. The medical implant structure of claim 1 , in which the first coating layer and the second coating layer are disposed essentially on top of each other.

4. The medical implant structure of claim 1 , wherein the first coating layer is deposited over and coats all the irregularities of the substrate except the most-protruding portions of said substrate on which the second coating layer is deposited.

5. The medical implant structure of claim 1 , wherein the first coating layer comprises hafnium (IV) oxide.

6. The medical implant structure of claim 1 , in which the first coating layer is an Atomic Layer Deposition (ALD) layer.

7. The medical implant structure of claim 1 , wherein said most-protruding portions of said substrate surface on which the second coating layer is deposited is an oxidized surface void of said first coating layer.

8. A joint implant comprising the medical implant structure as defined in claim 1 .

9. A method of manufacturing a medical implant structure as defined in claim 1 , wherein said first coating layer is established by an Atomic Layer Deposition (ALD) layer.

10. The method of claim 9 , further comprising removal of at least a part of the first coating layer deposited over the substrate, whereby at least a part of the substrate surface is rendered exposed, and depositing the second coating layer over the exposed substrate surface.

Assignees

• Picosun Oy

Inventors

• Oksala Niku
• Pudas Marko

Classifications

• A61L27/54

  Biologically active materials, e.g. therapeutic substances {(A61L27/227 takes precedence)} · CPC title

• A61L27/56

  Porous materials, {e.g. foams or sponges} · CPC title

• A61L2300/102

  Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates · CPC title

• A61L2300/606

  Coatings · CPC title

• A61F2250/006

  modular · CPC title