Collapsible catheter and method for calculating fractional flow reserve

Patent metadata

Field	Value
Publication number	US-11235124-B2
Application number	US-201715672792-A
Country	US
Kind code	B2
Filing date	Aug 9, 2017
Priority date	Aug 9, 2017
Publication date	Feb 1, 2022
Grant date	Feb 1, 2022

Abstract

A catheter for measuring a fractional flow reserve includes a proximal shaft, a distal shaft coupled to a distal portion of the proximal shaft, and a pressure sensor coupled to the distal shaft. The proximal shaft includes a distal portion configured to extend through a stenosis in a vessel. The distal portion of the proximal shaft includes a radially expanded configuration having a first diameter and a radially collapsed configuration having a second diameter, wherein the first diameter is larger than the second diameter. The distal shaft includes a guidewire lumen configured to receive therein.

First claim

What is claimed is:

1. A catheter for measuring a fractional flow reserve, the catheter comprising:
a shaft including a distal portion including a pressure sensor portion disposed at a distal end of the catheter and a collapsible portion extending proximally from the pressure sensor portion, the collapsible portion configured to be delivered through a stenosis in a vessel in a radially expanded configuration having a first diameter, the collapsible portion further having a radially collapsed configuration having a second diameter, wherein the first diameter is larger than the second diameter, and wherein the pressure sensor portion is not collapsible;
a guidewire lumen configured to receive a guidewire therein disposed through the pressure sensor portion of the distal portion of the shaft; and
a pressure sensor coupled to the pressure sensor portion of the distal portion of the shaft.

2. The catheter of claim 1 , wherein the collapsible portion of the distal portion of the shaft is inflatable using an inflation fluid.

3. The catheter of claim 2 , wherein the shaft includes an inflation lumen extending from a proximal end of the shaft to the collapsible portion of the distal portion of the shaft, and wherein the collapsible portion of the distal portion of the shaft includes an interior cavity in communication with the inflation lumen.

4. The catheter of claim 2 , wherein the collapsible portion of the distal portion of the shaft is configured to be inflated to the radially expanded configuration during delivery of the catheter through the stenosis, and wherein the collapsible portion of the distal portion of the shaft is configured to be in the radially collapsed configuration during measurement of a distal pressure distal of the stenosis using the pressure sensor.

5. The catheter of claim 2 , further comprising a guidewire exit port distal of the collapsible portion of the distal portion of the shaft.

6. The catheter of claim 1 , wherein a proximal portion of the shaft is radially expandable.

7. The catheter of claim 6 , wherein the proximal portion and the collapsible portion of the distal portion of the shaft are inflatable using an inflation fluid.

8. The catheter of claim 7 , wherein the proximal portion and the collapsible portion of the distal portion of the shaft include an interior cavity configured to receive an inflation fluid to inflate the proximal portion and the collapsible portion of the distal portion to the radially expanded configuration.

9. The catheter of claim 1 , wherein the collapsible portion of the distal portion of the shaft is formed of a shape memory material including a pre-set shape, wherein the pre-set shape is the radially collapsed configuration.

10. The catheter of claim 1 , further comprising at least one pressure sensor wire operably connected to the pressure sensor, wherein the at least one pressure sensor wire extends proximally from the pressure sensor through the shaft.

11. A catheter for measuring a fractional flow reserve, the catheter comprising:
a shaft including a distal portion, the distal portion of the shaft including a pressure sensor portion disposed at a distal end of the catheter and a collapsible portion extending proximally from the pressure sensor portion, wherein the collapsible portion includes a radially expanded configuration having a first diameter and a radially collapsed configuration having a second diameter, wherein the first diameter is larger than the second diameter;
a guidewire lumen extending through the collapsible portion and the pressure sensor portion of the distal portion of the shaft, the guidewire lumen configured to receive a guidewire therein, wherein the collapsible portion is in the radially expanded configuration when a guidewire is disposed in the guidewire lumen of the collapsible portion, wherein the collapsible portion is in the radially collapsed configuration when the guidewire is removed from the guidewire lumen of the collapsible portion, and wherein when the guidewire is removed from the pressure sensor portion, the pressure sensor portion does not radially collapse; and
a pressure sensor coupled to the pressure sensor portion of the distal portion of the shaft.

12. The catheter of claim 11 , further comprising a guidewire port proximal of the collapsible portion and distal of a hub of the catheter, the guidewire port being in communication with the guidewire lumen, wherein in the radially expanded configuration a guidewire is disposed through the guidewire port and into the guidewire lumen and extends within the guidewire lumen through the collapsible portion and the pressure sensor portion of the distal portion of the shaft.

13. The catheter of claim 11 , further comprising at least one pressure sensor wire operably connected to the pressure sensor, wherein the at least one pressure sensor wire extends proximally from the pressure sensor through the shaft.

14. The catheter of claim 11 , wherein the collapsible portion of the distal portion of the shaft is configured to be in the radially expanded configuration during delivery of the catheter through a stenosis, and wherein the collapsible portion of the distal portion of the shaft is configured to be in the radially collapsed configuration during measurement of a distal pressure distal of the stenosis using the pressure sensor.

15. The catheter of claim 11 , further comprising a guidewire exit port distal of the collapsible portion of the distal portion of the shaft.

16. The catheter of claim 11 , wherein the collapsible portion of the distal portion of the shaft is formed of a shape memory material including a pre-set shape, wherein the pre-set shape is the radially collapsed configuration.

17. The catheter of claim 16 , wherein the guidewire disposed in the collapsible portion causes the collapsible portion to expand to the radially expanded configuration and removing the guidewire from the collapsible portion causes the collapsible portion to return to the pre-set shape.

Assignees

• Medtronic Vascular Inc

Inventors

• Rogers Ronan
• Fleming Matthew
• O'Connell Barry
• Jones Timothy
• Hillas Joshua
• Callanan David
• Takaza Michael

Classifications

• A61B5/0215

  by means inserted into the body · CPC title

• A61B5/00

  Measuring for diagnostic purposes (radiation diagnosis A61B6/00; diagnosis by ultrasonic, sonic or infrasonic waves A61B8/00); Identification of persons · CPC title

• A61M25/0052

  Localized reinforcement, e.g. where only a specific part of the catheter is reinforced, for rapid exchange guidewire port · CPC title

• A61M2025/0183

  Rapid exchange or monorail catheters · CPC title

• A61B5/6876

  Blood vessel · CPC title