Physiological sensor delivery device and method

Patent metadata

Field	Value
Publication number	US-9011342-B2
Application number	US-201213418491-A
Country	US
Kind code	B2
Filing date	Mar 13, 2012
Priority date	Sep 11, 2008
Publication date	Apr 21, 2015
Grant date	Apr 21, 2015

Abstract

An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve, such as a fractional flow reserve (FFR) across a stenotic lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example. The sensing mechanism (sensor) can be a fiber optic pressure sensor, such as a MEMS-based FabryPerot fiber optic pressure sensor, for example, or could employ some other technology, e.g., MEMS capacitive or piezoresistive sensor.

First claim

What is claimed is:

1. A fluid injection system comprising:
fluid tubing adapted to provide fluid communication between the injection system and a patient, the fluid tubing including a contrast line, a saline line, and a patient line in selective fluid communication with the contrast and saline lines via a valve;
a pressure transducer in selective fluid communication with the patient line via the valve;
a guidewire;
a sensor delivery device that is slidably positionable over the guidewire, the sensor delivery device having a sensor that is positionable within the patient;
a control panel; and
a processor;
wherein the processor is adapted to receive:
(a) a first signal representative of blood pressure measured upstream of a location of interest in the patient by the pressure transducer, and
(b) a second signal generated by the sensor delivery device, the second signal representative of blood pressure measured downstream of the location of interest in the patient,

and wherein the control panel is adapted to display information derived from the first and second signals and the processor is adapted to calculate fractional flow reserve (FFR) based on a ratio of the first signal to the second signal.

2. The system of claim 1 wherein the control panel is adapted to display information related to the calculated FFR.

3. The system of claim 2 wherein the control panel provides an indication of whether the FFR is below a threshold value.

4. The system of claim 3 wherein the threshold value is about 0.75.

5. The system of claim 1 , wherein the sensor delivery device comprises:
a distal sleeve having a guidewire lumen for sliding over and receiving the guidewire; and
a proximal portion coupled to the distal sleeve, the proximal portion comprising a communication channel for communicating the second signal from the sensor to the processor of the injection system, the proximal portion being adapted to facilitate positioning of the sensor within a vascular structure of the patient.

6. The system of claim 5 , wherein the sensor is disposed on the distal sleeve.

7. The system of claim 5 , wherein the sensor is disposed on an outer surface of the proximal portion.

8. The system of claim 1 , wherein the sensor is fixedly coupled to the sensor delivery device.

9. The system of claim 1 , further comprising a guiding catheter, wherein the sensor delivery device is adapted to be deployed over the guidewire and through the guiding catheter.

Assignees

• Manstrom Dale R
• Raatikka Amy R
• Wilson Robert F
• Miller Edward R
• Pak Jung Kwon
• Acist Medical Sys Inc

Inventors

• Manstrom Dale R
• Raatikka Amy R
• Wilson Robert F
• Miller Edward R
• Pak Jung Kwon

Classifications

• A61M25/0067

  characterised by the distal end, e.g. tips (A61M25/0054, A61M25/04 take precedence; balloon catheters A61M25/10) · CPC title

• A61M2025/0002

  with a pressure sensor at the distal end · CPC title

• A61B5/01

  Measuring temperature of body parts {; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue} (clinical contact thermometers G01K13/20) · CPC title

• A61B5/14552

  Details of sensors specially adapted therefor · CPC title

• A61B5/0017

  transmitting optical signals · CPC title