Inhaler

Patent metadata

Field	Value
Publication number	US-11224705-B2
Application number	US-201716076879-A
Country	US
Kind code	B2
Filing date	Feb 20, 2017
Priority date	Feb 24, 2016
Publication date	Jan 18, 2022
Grant date	Jan 18, 2022

Abstract

An inhaler for inhalation of a formulation in powder form includes: a magazine which is rotatable and contains pre-dosed doses of the formulation in capsules, a housing which is substantially round or disc-shaped, the housing having a housing part in which the rotatable magazine is disposed, where the housing part is fixedly coupled to the rotatable magazine, and is removable from the housing in order to facilitate replacement of the magazine by inserting a new magazine.

First claim

The invention claimed is:

1. An inhaler ( 1 ) for inhalation of a formulation ( 2 ) in powder form, comprising:
a magazine ( 5 ) which is rotatable and contains pre-dosed doses of the formulation ( 2 ) in capsules ( 3 ),
a housing ( 17 ) which is substantially flat or disc-shaped within a main plane (E), the housing ( 17 ) having a housing part ( 24 ) in which the rotatable magazine ( 5 ) is disposed, and
capsule chambers ( 4 ) within the magazine ( 5 ), each containing a respective one of the capsules ( 3 ),
wherein at least one of the capsules ( 3 ) and the capsule chambers ( 4 ) are secured in the magazine ( 5 ) by a single securing element ( 14 ) in such a way that dispensing respective doses of the formulation ( 2 ) from the respective capsules ( 3 ) is carried out without removal of the securing element ( 14 ) from the capsule chambers ( 4 ),
wherein the securing element ( 14 ) is in the form of an annularly extending element, including at least one of a wire and clamping ring,
wherein the housing part ( 24 ) is fixedly coupled to the rotatable magazine ( 5 ), and is removable from the housing ( 17 ) in order to facilitate replacement of the magazine ( 5 ) by inserting a new magazine, and
the housing part ( 24 ) and the magazine ( 5 ) are inserted into the housing ( 17 ) of the inhaler ( 1 ) in a direction, which is parallel to a main plane (E) of the magazine ( 5 ) and the housing ( 17 ).

2. The inhaler according to claim 1 , wherein the housing part ( 24 ) forms a circumferential portion along the magazine ( 5 ) and/or housing ( 17 ).

3. The inhaler according to claim 1 , wherein the direction is a radial direction of the main plane (E) of the magazine ( 5 ) and the housing ( 17 ).

4. The inhaler according to claim 1 , the housing part ( 24 ) has a first coding element ( 27 ) and the housing ( 17 ) has a second coding element ( 28 ), wherein the first and second coding elements ( 27 , 28 ) only engage in one another when a coding thereof matches, so that the magazine ( 5 ) and the housing part ( 24 ) can only be inserted into the housing ( 17 ) of the inhaler ( 1 ) when the coding matches.

5. The inhaler according to claim 1 , further comprising:
a mouthpiece operable to deliver the formulation ( 2 ) to a user when dispensed;
a cover ( 18 ) for the mouthpiece ( 15 ), the cover ( 18 ) being coupled to the magazine ( 5 ) in such a way that at least one of:
a pivoting of the cover ( 18 ) operates to open and close the mouthpiece ( 15 ) and operates to rotationally index the magazine ( 5 ) for a next dose, and
the cover ( 18 ) is pivotable for opening and closing of the mouthpiece, where pivoting the cover ( 18 ) biases a spring element ( 52 ) for further movement of the magazine ( 5 ).

6. The inhaler according to claim 1 , further comprising:
capsule chambers ( 4 ) within the magazine ( 5 ), each containing a respective one of the capsules ( 3 ), and each including at least one needle opening ( 8 ),
an opening device ( 6 ) having at least one needle ( 7 ) for piercing the respective capsules ( 3 ) within the respective capsule chambers ( 4 ) through the at least one needle opening ( 8 ), and
a closing device for closing the at least one needle opening ( 8 ) of a given one of the capsule chambers ( 4 ) during the inhalation of formulation ( 2 ) from the respective capsule ( 3 ) within such given one of the capsule chambers ( 4 ), wherein the closing device comprises a sealing element ( 50 ) which is applied externally to the given one of the capsule chambers ( 4 ) for closing the at least one needle opening ( 8 ) thereof during the inhalation of the formulation ( 2 ).

7. The inhaler according to claim 6 , wherein at least one of:
the sealing element ( 50 ) is flat or plate-shaped,
the sealing element ( 50 ) has an opening for freeing the at least one needle opening ( 8 ),
the sealing element ( 50 ) is movable or displaceable, with at least one of the opening device ( 6 ) and a mouthpiece ( 15 ) of the inhaler ( 1 ), transversely with respect to the at least one needle opening ( 8 ),
the sealing element ( 50 ) is applied automatically to the capsule chamber ( 4 ) or the at least one needle opening ( 8 ) from an exterior during inhalation, and
the sealing element ( 50 ) is resiliently biased against the capsule chamber ( 4 ) or the at least one needle opening ( 8 ) from the exterior.

8. The inhaler according to claim 1 ,
wherein:
the capsule chambers ( 4 ) are arranged in a prefabricated, annular manner, into the magazine ( 5 ),
and
the capsules ( 3 ) are elongated and are oriented with respective longitudinal axes thereof obliquely oriented with respect to an axis of rotation (D) of the magazine ( 5 ).

9. A magazine ( 5 ) for an inhaler ( 1 ) for inhalation of a formulation ( 2 ) in powder form, comprising:
capsule chambers ( 4 ) within the magazine ( 5 ), each containing a respective one of the capsules ( 3 ), and each one of the capsules ( 3 ) containing a dose of the formulation ( 2 ), wherein:
the capsule chambers ( 4 ) are arranged in a prefabricated, annular manner, into the magazine ( 5 ),
at least one of the capsules ( 3 ) and the capsule chambers ( 4 ) are secured in the magazine ( 5 ) by a single securing element ( 14 ) in such a way that dispensing respective doses of the formulation ( 2 ) from the respective capsules ( 3 ) is carried out without removal of the securing element ( 14 ) from the capsule chambers ( 4 ),
the securing element ( 14 ) is in the form of an annularly extending element, including at least one of a wire and clamping ring, and
the capsules ( 3 ) are elongated and are oriented with respective longitudinal axes thereof obliquely oriented with respect to an axis of rotation (D) of the magazine ( 5 ).

10. The magazine according to claim 9 , wherein the magazine ( 5 ) has an integral or multi-part support ( 33 ) to accommodate the capsule chambers ( 4 ).

11. The magazine according to claim 10 , wherein the support ( 33 ) is flexible or rubber-elastic.

12. The magazine according to claim 10 , wherein the support ( 33 ) is substantially rigid.

13. The magazine according to claim 9 , wherein the securing element ( 14 ) is arranged on an outer circumference of the magazine ( 5 ).

14. The magazine according to claim 9 , wherein the capsules ( 3 ) and/or capsule chambers ( 4 ) are oriented substantially radially.

15. The magazine according to claim 9 , wherein piercing or needle openings ( 8 ) are pre-formed in the capsule chambers ( 4 ) or are configured as walled opening sites that are pierceable.

16. The magazine according to claim 9 , wherein the capsule chambers ( 4 ) have needle openings ( 8 ) which are self-closing.

Assignees

• Boehringer Ingelheim Int

Inventors

• Holakovsky Holger
• Besseler Jens
• Frentzel-Beyme Jessica
• Herrmann Frank

Classifications

• A61M15/005

  the dosages being arranged on a cylindrical surface · CPC title

• A61M2205/6045

  having complementary physical shapes for indexing or registration purposes · CPC title

• A61M15/0035

  Piercing means · CPC title

• A61M2202/064

  Powder · CPC title

• A61M15/0026

  Hinged caps · CPC title