Antimicrobial dental restoratives containing coconut oil and/or derivatives of coconut oil

Patent metadata

Field	Value
Publication number	US-11202736-B2
Application number	US-201815897724-A
Country	US
Kind code	B2
Filing date	Feb 15, 2018
Priority date	Feb 15, 2018
Publication date	Dec 21, 2021
Grant date	Dec 21, 2021

Abstract

A dental restorative based on a cured dental composite containing coconut oil and/or a derivative of coconut oil. The dental restorative also includes a polymerizable monomer, a filler, and a polymerization initiator. Methods of preventing or reducing growth of microorganisms and inhibiting formation of biofilms are also described.

First claim

The invention claimed is:

1. A dental composite, comprising:
a polymerizable monomer;
a filler in an amount of 40-75 wt % based on a total weight of the dental composite;
a polymerization initiator; and
a chemical derivative of a coconut oil in an amount ranging from 0.1 wt % to 20 wt % based on the total weight of the dental composite, wherein the chemical derivative of coconut oil is a reaction product of coconut oil and hydrogen peroxide and has an oxygen content that is greater by 0.5-5 wt % in comparison to the coconut oil before reacting with hydrogen peroxide.

2. The dental composite of claim 1 , consisting essentially of:
the polymerizable monomer;
the filler in an amount of 40-75 wt %;
the polymerization initiator; and
the chemical derivative of the coconut oil in an amount ranging from 0.1 wt % to 20 wt %;
wherein the weight percentages are based on a total weight of the dental composite.

3. The dental composite of claim 1 , wherein the polymerizable monomer is at least one selected from the group consisting of a methacrylate monomer, an acrylate monomer, an epoxy monomer, and a vinyl monomer.

4. The dental composite of claim 3 , wherein the polymerizable monomer is a methacrylate monomer.

5. The dental composite of claim 4 , wherein the methacrylate monomer is at least one selected from the group consisting of bisphenol A-glycidyl methacrylate (bis-GMA), urethane dimethacrylate (UDMA), triethylene glycol dimethacrylate (TEGDMA), ethoxylated bisphenol A dimethacrylate (EBPADMA), and 2-hydroxyethyl methacrylate (HEMA).

6. The dental composite of claim 1 , wherein the filler is at least one selected from the group consisting of a glass filler, a ceramic filler, and a polymer-based filler.

7. The dental composite of claim 1 , wherein the filler is at least one selected from the group consisting of silica, zirconia, and aluminosilicate.

8. The dental composite of claim 1 , wherein the polymerization initiator is a free radical initiator.

9. The dental composite of claim 8 , wherein the free radical initiator is at least one selected from the group consisting of camphorquinone, an acyl phosphine oxide, an azo compound, and an organic peroxide.

10. A dental restoration, comprising a cured dental composite of claim 1 .

11. The dental restoration of claim 10 , which has a flexural strength of about 70 MPa to about 150 MPa.

12. The dental restoration of claim 10 , which has a Vickers hardness number HV of about 60 to about 100.

13. The dental restoration of claim 10 , comprising the filler in an amount of 65-75 wt %.

Assignees

• Univ Imam Abdulrahman Bin Faisal

Inventors

• Alsheikh Rasha Numan Ali
• Almasoud Naif Nasser

Classifications

• A61K6/71

  Fillers · CPC title

• A61K9/0053

  Mouth and digestive tract, i.e. intraoral and peroral administration · CPC title

• A61K6/62

  Photochemical radical initiators · CPC title

• A61K6/77

  Glass · CPC title

• A61K6/69 Primary

  Medicaments · CPC title