Coatings with crystallized active agent(s) and methods
US-9427501-B2 · Aug 30, 2016 · US
Formulation
US2017304156A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2017304156-A1 |
| Application number | US-201515514058-A |
| Country | US |
| Kind code | A1 |
| Filing date | Sep 4, 2015 |
| Priority date | Sep 26, 2014 |
| Publication date | Oct 26, 2017 |
| Grant date | — |
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- Title
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Abstract
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The present invention relates to a hydrogel formulation in which the solid phase is composed of a continuous net work of siloxane bonds and one or more calcium phosphate phases doped with one or more metal dopants.
First claim
Opening claim text (preview).
1 . A hydrogel formulation comprising: a solid phase composed of a continuous network of siloxane bonds and one or more calcium phosphate phases doped with one or more metal dopants; and an aqueous phase, or a precursor or anhydrate thereof. 2 . The hydrogel formulation as claimed in claim 1 wherein the one or more metal dopants is or includes ions of a rare earth element. 3 . The hydrogel formulation as claimed in claim 2 wherein the rare earth element is selected from the group consisting of erbium, cerium and ytterbium. 4 . The hydrogel formulation as claimed in claim 1 , wherein the one or more metal dopants is or includes aluminium ions. 5 . The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases are fluoride ion-substituted. 6 . The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases includes fluorapatite. 7 . The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases are fluoride ion-substituted and the one or more metal dopants is or includes aluminium ions. 8 . The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases are fluoride ion-substituted and the one or more metal dopants is or includes ions of a rare earth element. 9 . The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases are fluoride ion-substituted and the one or more metal dopants is or includes aluminium ions and ions of a rare earth element. 10 . The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases is or includes synthetic hydroxyapatite or a synthetic precursor thereof. 11 . The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases is or includes a synthetic mineral of formula CaHPO 4 .xH 2 O (wherein x is 0, 1 or 2). 12 . The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases include monetite which is the predominant calcium phosphate phase. 13 . The hydrogel formulation as claimed in claim 1 , wherein the one or more calcium phosphate phases include brushite which is the predominant calcium phosphate phase. 14 . The hydrogel formulation as claimed in claim 1 , wherein the solid phase is further composed of chitosan. 15 . The hydrogel formulation as claimed in claim 1 , obtained or obtainable by a process comprising: (a) preparing an aqueous mixture of a calcium ion-containing solution, a phosphate ion-containing solution and a metal dopant-containing solution in the presence of the siloxane network precursor; (b) causing the formation of the solid phase in the aqueous mixture; and (c) isolating the hydrogel formulation. 16 .- 30 . (canceled)
Assignees
Inventors
Classifications
Rare earth metals · CPC title
Phosphate cements (apatite A61K6/838) · CPC title
- A61K6/20Primary
Protective coatings for natural or artificial teeth, e.g. sealings, dye coatings or varnish · CPC title
Medicaments · CPC title
Phosphorus compounds, e.g. apatite · CPC title
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Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US2017304156A1 cover?
- The present invention relates to a hydrogel formulation in which the solid phase is composed of a continuous net work of siloxane bonds and one or more calcium phosphate phases doped with one or more metal dopants.
- Who is the assignee on this patent?
- Univ Leeds Innovations Ltd, Univ Court Univ St Andrews
- What technology area does this patent fall under?
- Primary CPC classification A61K6/20. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Thu Oct 26 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).