Substituted pyrrolo, -furano, and cyclopentylpyrimidines having antimitotic and/or antitumor activity and methods of use thereof
US-8946239-B2 · Feb 3, 2015 · US
US11111252B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11111252-B2 |
| Application number | US-202016947651-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 11, 2020 |
| Priority date | Aug 8, 2014 |
| Publication date | Sep 7, 2021 |
| Grant date | Sep 7, 2021 |
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The present invention discloses a compound of the formula:and optionally comprising a pharmaceutically acceptable salt or hydrate thereof. A method of treating a patient having cancer or a disease comprising administering to a patient an effective amount of the compound or pharmaceutically acceptable salt or hydrate thereof.
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What is claimed is: 1. A compound of the formula: wherein R is 2-OCH 3 , 3-OCH 3 , 4-OCH 3 , or 3,4-diOCH 3 , or a pharmaceutically acceptable salt or hydrate thereof. 2. A pharmaceutical composition comprising a therapeutically effective amount of a compound of the formula: wherein R is 2-OCH 3 , 3-OCH 3 , 4-OCH 3 , or 3,4-diOCH 3 , and optionally comprising a pharmaceutically acceptable salt or hydrate thereof. 3. The pharmaceutical composition of claim 1 comprising at least one pharmaceutical carrier.
condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone · CPC title
Non-condensed quinolines and containing further heterocyclic rings · CPC title
containing two hetero rings · CPC title
Two nitrogen atoms · CPC title
containing two hetero rings · CPC title
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