Alpha-1,3-glucan graft copolymers

Patent metadata

Field	Value
Publication number	US-11098334-B2
Application number	US-201816218518-A
Country	US
Kind code	B2
Filing date	Dec 13, 2018
Priority date	Dec 14, 2017
Publication date	Aug 24, 2021
Grant date	Aug 24, 2021

Abstract

Compositions are disclosed herein comprising a graft copolymer that comprises: (i) a backbone comprising dextran that has been modified with about 1%-25% alpha-1,2 branches, and (ii) one or more alpha-1,3-glucan side chains comprising at least about 50% alpha-1,3 glycosidic linkages. Further disclosed are reactions for producing such graft copolymers, as well as their use in derivatives, films and various other applications.

First claim

What is claimed is:

1. A composition comprising a graft copolymer, or an ether- or ester-derivative thereof, wherein said graft copolymer comprises:
(i) a backbone comprising a dextran that has been modified with about 1%-25% alpha-1,2 branches, wherein the weight-average degree of polymerization (DPw) of the backbone is 10 to 500, and
(ii) one or more alpha-1,3-glucan side chains comprising at least about 50% alpha-1,3 glycosidic linkages.

2. The composition of claim 1 , wherein said dextran is substantially linear dextran that has been modified with about 1%-25% alpha-1,2 branches.

3. The composition of claim 1 , wherein the dextran has been modified with about 5%-20% alpha-1,2 branches.

4. The composition of claim 1 , wherein the dextran has been modified with 5%-15% alpha-1,2 branches.

5. The composition of claim 1 , wherein the DPw of the backbone is about 10 to 200.

6. The composition of claim 1 , wherein the alpha-1,3-glucan side chains comprise at least about 90% alpha-1,3 glycosidic linkages.

7. The composition of claim 1 , wherein the DP or DPw of said one or more alpha-1,3-glucan side chains is at least about 10.

8. The composition of claim 1 , wherein the composition comprises the graft copolymer.

9. The composition of claim 1 , wherein the composition comprises the ether-derivative of the graft copolymer.

10. The composition of claim 1 , wherein the composition is a household care product, personal care product, industrial product, pharmaceutical product, or food product.

11. The composition of claim 1 , wherein the composition is a film or coating.

12. The composition of claim 1 , wherein said graft copolymer comprises one or two of said alpha-1,3-glucan side chains.

13. The composition of claim 1 , wherein the composition is a detergent composition.

14. A method of producing a graft copolymer, said method comprising:
(a) contacting at least (i) water, (ii) sucrose, (iii) dextran that has been modified with about 1%-25% alpha-1,2 branches and having a weight-average degree of polymerization (DPw) of 10 to 500, and (iv) a glucosyltransferase enzyme that synthesizes alpha-1,3-glucan comprising at least about 50% alpha-1,3 glycosidic linkages,
whereby a graft copolymer according to the composition of claim 1 is produced; and

(b) optionally, isolating the graft copolymer produced in step (a).

15. The method of claim 14 , wherein said dextran is substantially linear dextran that has been modified with about 1%-25% alpha-1,2 branches.

16. The method of claim 14 , wherein the dextran has been modified with about 5%-20% alpha-1,2 branches.

17. The method of claim 14 , wherein the dextran has been modified with 5%-15% alpha-1,2 branches.

18. The method of claim 14 , wherein the dextran has a DPw of 10 to 200.

19. The method of claim 14 , wherein said graft copolymer comprises one or two of said alpha-1,3-glucan side chains.

20. A method for producing a film or coating, said method comprising:
(a) dissolving the graft copolymer, or ether- or ester-derivative thereof, of claim 1 in a solvent to provide a solution;
(b) contacting the solution with a surface; and
(c) removing the solvent to form a film or coating.

21. The method of claim 20 , wherein the solution of (a) comprises less than 15 wt % of the graft copolymer or ether- or ester-derivative thereof.

22. A method of producing alpha-1,3-glucan, said method comprising:
(a) contacting at least (i) water, (ii) sucrose, (iii) dextran that has been modified with about 1%-50% alpha-1,2 branches and having a weight-average degree of polymerization (DPw) of 10 to 500, and (iv) a glucosyltransferase enzyme that synthesizes alpha-1,3-glucan comprising at least about 50% alpha-1,3 glycosidic linkages, thereby providing an enzymatic reaction,
whereby alpha-1,3-glucan comprising at least about 50% alpha-1,3 glycosidic linkages is produced, and

(b) optionally, isolating the alpha-1,3-glucan produced in step (a).

Assignees

• Nutrition & Biosciences Usa 4 Inc

Inventors

• Guan Rong
• Ohane James Joshua
• Iltchenko Nikita
• Brun Yefim
• Mccauley Brian
• Howe Laurie A
• Li Yougen

Classifications

• C08L5/02 Primary

  Dextran; Derivatives thereof · CPC title

• C12P19/18

  produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins · CPC title

• C08J2305/02

  Dextran; Derivatives thereof · CPC title

• C11D3/3707

  Polyethers, e.g. polyalkyleneoxides · CPC title

• C08J2305/00

  Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00 · CPC title