Silicone hydrogel composition

Patent metadata

Field	Value
Publication number	US-11046802-B2
Application number	US-202016889768-A
Country	US
Kind code	B2
Filing date	Jun 1, 2020
Priority date	May 25, 2017
Publication date	Jun 29, 2021
Grant date	Jun 29, 2021

Abstract

The present invention provides a silicone hydrogel composition. The silicone hydrogel composition includes a water-soluble silicone macromere, a hydrophilic monomer, a crosslinker, an initiator and an organic solvent. The water-soluble silicone macromere, the hydrophilic monomer, the crosslinker and the initiator is respectively in the amount of 50-80 wt %, 19-50 wt %, 0.1-1.5 wt % and 0.1-1 wt % based on the total weight of the silicone hydrogel composition.

First claim

What is claimed is:

1. A silicone hydrogel composition, comprising:
a water-soluble silicone macromer in the amount of 50-80 wt % based on the total weight of the silicone hydrogel composition, wherein the water-soluble silicone macromer has a structure presented by formula (1) below:
E-(M 1 ) x -(M 2 ) y   formula (1);

wherein M 1 is a repeating unit comprises

formula (9), or a combination thereof, wherein formula (8) and formula (9) has a number-averaged molecular weight of less than 1500, p is an integer of 0-4, q is 0 or 1, k is an integer of 4-20, and R 2 is C1-C10 alkyl group;
M 2 is a repeating unit comprises

of molecular weight less than 1000, or a combination thereof, wherein a is an integer of 1-21, and a weight ratio of (M 1 ) x to (M 2 ) y is from 30:70 to 50:50;
E is a terminal group comprises

wherein a symbol “*” in formula (20)-(23) indicates a position to be linked to M 1 ;
x is an integer of 1-20;
y is an integer of 1-20;
a number-average molecular weight (Mn) of the water-soluble silicone macromer ranges from 2000 to 5000; and
an aqueous solution composed of 0.5 wt % of the water-soluble silicone macromer and water has a light transmittance of greater than 20% at a wavelength of 450 nm;
a hydrophilic monomer in the amount of 19-50 wt % based on the total weight of the silicone hydrogel composition;
a crosslinker in the amount of 0.1-1.5 wt % based on the total weight of the silicone hydrogel composition;
an initiator in the amount of 0.1-1 wt % based on the total weight of the silicone hydrogel composition; and
an organic solvent.

2. The silicone hydrogel composition of claim 1 , wherein the hydrophilic monomer is selected from the group consisting of N,N-dimethyl acrylamide, N,N-diethyl acrylamide, N-isopropyl acrylamide, N-vinyl pyrrolidone, N-vinyl-N-methyl acetamide, 2-hydroxyethyl methacrylate, 3-hydroxypropyl methacrylate, glycerol methacrylate, methacrylic acid, acrylic acid, 2-methacryloyloxyethyl phosphorylcholine, and a combination thereof.

3. The silicone hydrogel composition of claim 1 , wherein the crosslinker is selected from the group consisting of ethylene glycol dimethacrylate, triethylene glycol dimethacrylate, tetraethylene glycol dimethacrylate, trimethylolpropane trimethacrylate, pentaerythritol tetramethacrylate, bisphenol A dimethacrylate, methylenebis(methacrylamide), divinyl ether, divinyl sulfone, divinylbenzene, trivinylbenzene, triallyl isocyanurate, triallyl phthalate, diallyl phthalate, allyl methacrylate, and a combination thereof.

4. The silicone hydrogel composition of claim 1 , wherein the initiator is a thermal initiator or a photo initiator.

5. The silicone hydrogel composition of claim 1 , wherein the organic solvent is selected from the group consisting of n-butanol, t-butanol, n-pentyl alcohol, t-amyl alcohol, n-hexanol, 3-methoxy-1-butanol, methyl cabitol, ethyl carbitol, propyl carbitol, butyl carbitol and a combination thereof.

6. The silicone hydrogel composition of claim 1 , further comprising a tint monomer or a tint compound.

7. The silicone hydrogel composition of claim 1 , further comprising a UV-blocking monomer, and the UV-blocking monomer is a benzotrizole-type monomer.

Assignees

• Pegavision Corp

Inventors

• Lai Yu-Chin
• Kuan Ting-Chun
• Kung Hsiang-Ho
• Yeh Min-Tzung
• Yang Ching-Wen
• Hsu Tsung-Kao

Classifications

• C08F290/046 Primary

  Polymers of unsaturated carboxylic acids or derivatives thereof · CPC title

• C08F230/08

  containing silicon · CPC title

• C08F290/062 Primary

  Polyethers · CPC title

• C08F290/068

  Polysiloxanes · CPC title

• C08G18/289

  containing silicon · CPC title