Esters of 2-deoxy-monosaccharides with anti proliferative activity

US11026960B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11026960-B2
Application numberUS-201816229338-A
CountryUS
Kind codeB2
Filing dateDec 21, 2018
Priority dateApr 5, 2013
Publication dateJun 8, 2021
Grant dateJun 8, 2021

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Compounds and methods of using the same to inhibit glycolysis and treat cancer and other diseases are disclosed.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of treating brain or pancreatic cancer in a patient in need thereof comprising administering a therapeutically effective amount of one or more compounds of the Formula I: or a salt thereof, wherein: each R 1 , R 2 , R 3 and R 4 are independently H, or C(O)R 5 ; at least two of R 1 , R 2 , R 3 and R 4 is C(O)R 5 ; and each R 5 is independently selected from C 3 -C 7 straight- or branched-chain alkyl, C 4 -C 10 alkylcycloalkyl, and C 3 -C 7 cycloalkyl. 2. The method of claim 1 , wherein R 2 and R 3 are C(O)R 5 . 3. The method of claim 1 , wherein the compound is chosen from: 4. A method of treating brain or pancreatic cancer in a patient in need thereof comprising administering a therapeutically effective amount of the compound 5. A method of treating brain or pancreatic cancer in a patient in need thereof comprising administering a therapeutically effective amount of the compound

Assignees

Inventors

Classifications

  • specific for metastasis · CPC title

  • Esters of saccharides · CPC title

  • specific for leukemia · CPC title

  • Antineoplastic agents · CPC title

  • Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

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Frequently asked questions

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What does patent US11026960B2 cover?
Compounds and methods of using the same to inhibit glycolysis and treat cancer and other diseases are disclosed.
Who is the assignee on this patent?
Univ Texas, Conrad Kim
What technology area does this patent fall under?
Primary CPC classification A61K31/7024. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jun 08 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).