Venous valve prostheses

Patent metadata

Field	Value
Publication number	US-10973640-B2
Application number	US-201816194961-A
Country	US
Kind code	B2
Filing date	Nov 19, 2018
Priority date	Dec 3, 2015
Publication date	Apr 13, 2021
Grant date	Apr 13, 2021

Abstract

A venous valve prosthesis includes a frame and a prosthetic valve coupled to the frame. With the venous valve prosthesis implanted in a vein, the prosthetic valve includes a closed configuration wherein an outer surface of the prosthetic valve is in contact with a wall of the vein around a circumference of the prosthetic valve to prevent blood from flowing past the prosthetic valve between the wall of the vein and the outer surface of the prosthetic valve. The prosthetic valve is configured to move to an open configuration such that at least a portion of an outer wall of the prosthetic valve partially collapses away from the wall of the vein in response to antegrade blood flow through the vein to enable blood flow between the outer surface of the prosthetic valve and the wall of the vein.

First claim

What is claimed is:

1. A venous valve prosthesis comprising:
a frame comprising a valve section and a stabilizing section, wherein the stabilizing section is configured to anchor the venous valve prosthesis within a vessel of a patient, the valve section being configured to compress radially inward from a radially expanded configuration to a radially compressed configuration, wherein the stabilizing section is configured to remain expanded when the valve section is in the radially expanded configuration and when the valve section is in the radially compressed configuration; and
a prosthetic valve coupled to the frame, wherein when the valve section is in the radially expanded configuration, the valve section applies a radially outward force on the prosthetic valve, and wherein radial compression of the valve section from the radially expanded configuration to the radially compressed configuration is configured to move the prosthetic valve from a closed valve configuration to an open valve configuration,
wherein when the venous valve prosthesis is implanted in a vessel and the prosthetic valve is in the open valve configuration, the venous valve prosthesis is configured to enable antegrade blood flow between an outer surface of the prosthetic valve and a wall of the vessel, and when the prosthetic valve in the closed valve configuration, an outer surface of the prosthetic valve is in contact with the wall of the vessel around a perimeter of the prosthetic valve to prevent blood from flowing past the prosthetic valve between the wall of the vessel and the outer surface of the prosthetic valve.

2. The venous valve prosthesis of claim 1 , wherein the stabilizing section is configured to cause at least a portion of the outer surface of the prosthetic valve to contact the wall in both the open valve configuration and the closed valve configuration.

3. The venous valve prosthesis of claim 1 , wherein the prosthetic valve defines slits, and wherein in the open valve configuration, the slits are opened by the compression of the valve section to enable antegrade blood flow upstream of the slits and through the slits.

4. The venous valve prosthesis of claim 1 , wherein the frame comprises a plurality of struts and openings defined between the plurality of struts.

5. The venous valve prosthesis of claim 1 , wherein the prosthetic valve is coupled to the valve section of the frame.

6. The venous valve prosthesis of claim 1 , wherein the frame is a self-expanding frame.

7. The venous valve prosthesis of claim 6 , wherein the stabilizing section of the frame is configured to exert a first radially outward force that is greater than a second radially outward force exerted by the valve section of the frame.

8. The venous valve prosthesis of claim 1 , wherein the prosthetic valve includes a tapered surface and a non-tapered surface.

9. The venous valve prosthesis of claim 8 , wherein the non-tapered surface includes a substantially cylindrical surface adjacent a larger end of the tapered surface.

10. The venous valve prosthesis of claim 9 , wherein the substantially cylindrical surface defines slits, wherein in the open valve configuration, the slits are opened by the compression of the valve section to enable antegrade blood flow upstream of the slits and through the slits.

11. The venous valve prosthesis of claim 1 , wherein the valve section is configured to compress radially inward from the radially expanded configuration to the radially compressed configuration in response to a pressure exerted within the vessel to push blood in a downstream direction, and wherein the stabilizing section is configured to not radially compress in response to the pressure.

12. The venous valve prosthesis of claim 1 , wherein the prosthetic valve defines an opening through a middle portion of the prosthetic valve, wherein the opening is open in both the open valve configuration and the closed valve configuration.

13. The venous valve prosthesis of claim 1 , wherein the valve section includes a hub at an upstream end of the valve section and a plurality of struts extending in a downstream direction from the hub and radially outward from the hub.

14. The venous valve prosthesis of claim 1 , wherein the valve section and the stabilizing section are part of a single, unitary frame.

15. The venous valve prosthesis of claim 1 , wherein the valve section and the stabilizing section are separate pieces that are joined together.

16. The venous valve prosthesis of claim 1 , wherein the prosthetic valve is disposed about an exterior of the frame.

17. The venous valve prosthesis of claim 1 , wherein the prosthetic valve is disposed within an interior of the frame.

18. The venous valve prosthesis of claim 1 , wherein the frame is a balloon-expandable frame.

19. A venous valve prosthesis comprising:
a frame comprising a valve section and a stabilizing section, wherein the stabilizing section is configured to anchor the venous valve prosthesis within a vessel of a patient, and wherein when the venous valve prosthesis is implanted in a vessel, the valve section is configured to compress radially inward from a radially expanded configuration to a radially compressed configuration in response to a pressure exerted within the vessel to push blood through the vessel, the stabilizing section being configured to not radially compress in response to the pressure; and
a prosthetic valve coupled to the frame such that radial compression of the valve section from the radially expanded configuration to the radially compressed configuration moves the prosthetic valve from a closed valve configuration to an open valve configuration, wherein when the valve section is in the radially expanded configuration, the valve section applies a radially outward force on the prosthetic valve,
wherein when the venous valve prosthesis is implanted in the vessel and the prosthetic valve is in the open valve configuration, the venous valve prosthesis is configured to enable antegrade blood flow between an outer surface of the prosthetic valve and a wall of the vessel, and when the prosthetic valve in the closed valve configuration, an outer surface of the prosthetic valve is in contact with the wall of the vessel around a perimeter of the prosthetic valve to prevent blood from flowing past the prosthetic valve between the wall of the vessel and the outer surface of the prosthetic valve.

20. The venous valve prosthesis of claim 19 , wherein the prosthetic valve defines an opening through a middle portion of the prosthetic valve, wherein the opening is open in both the open valve configuration and the closed valve configuration.

21. A method comprising:
delivering a venous valve prosthesis to a site in a vessel of a patient, wherein the venous valve prosthesis includes a frame and a prosthetic valve coupled to the frame, the frame comprising a valve section and a stabilizing section; and
deploying the venous valve prosthesis at the site in the vessel, wherein the stabilizing section is configured to anchor the venous valve prosthesis within the vessel, the valve section being configured to compress radially inward from a radially expanded configuration to a radially compressed configuration, wherein the stabilizing section is configured to remain expanded when the valve section is in the radially expanded configuration and when the valve section is in the radially compressed configuration;
wherein when the valve section is in the radially expanded configuration, the valve section appli

Assignees

• Medtronic Vascular Inc

Inventors

• Argentine Jeffery
• Malsbary Todd
• Perkins Keith
• Rowe Travis

Classifications

• A61F2230/001

  Figure-8-shaped, e.g. hourglass-shaped · CPC title

• A61F2/2418

  Scaffolds therefor, e.g. support stents · CPC title

• A61F2230/0067

  conical · CPC title

• A61F2230/0097

  Harpoon-shaped · CPC title

• A61F2/2436

  Deployment by retracting a sheath · CPC title