Inactivation of gram-positive bacteria
US-9839706-B2 · Dec 12, 2017 · US
US10953117B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10953117-B2 |
| Application number | US-201715807488-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 8, 2017 |
| Priority date | Jul 29, 2005 |
| Publication date | Mar 23, 2021 |
| Grant date | Mar 23, 2021 |
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A method for inactivating medically important Gram-positive bacteria including Methicillin-resistant Staphylococcus aureus (MRSA), Coagulase-Negative Staphylococcus (CONS), Streptococcus, Enterococcus and Clostridium species, comprising exposure to visible light, and in particular light within the wavelength range 400-500 nm.
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The invention claimed is: 1. A method for disinfecting air, contact surfaces, or materials by inactivating bacteria from one or more pathogenic Gram-positive bacterial species in the air, on the contact surfaces, or on the materials, said method comprising exposing the one or more pathogenic Gram-positive bacterial species to white light containing blue light without using a photosensitizer, wherein the one or more pathogenic Gram-positive bacterial species are selected from the group consisting of Streptococcus and Clostridium species, wherein at least a portion of the blue light that inactivates the one or more Gram-positive bacterial species consists of wavelengths in the range 400-500 nm, and wherein the method is performed outside of the human body and the contact surfaces or the materials are non-living. 2. The method according to claim 1 , wherein the portion of the blue light that inactivates the one or more Gram-positive bacterial species consists of wavelengths in the range 400-450 nm. 3. The method of claim 1 , wherein the portion of the blue light that inactivates the one or more Gram-positive bacterial species consists of wavelengths in the range 400-420 nm. 4. The method of claim 1 , wherein the portion of the blue light that inactivates the one or more Gram-positive bacterial species has a wavelength of about 405 nm. 5. A method for disinfecting air, contact surfaces, or materials by inactivating one or more pathogenic Gram-positive bacterial species in the air, on the contact surfaces, or on the materials, said method comprising exposing the one or more pathogenic Gram-positive bacterial species to white light containing blue light without using a photosensitizer, wherein the Gram-positive bacterial species are selected from the group consisting of Streptococcus and Clostridium species and further wherein at least a portion of the blue light that inactivates the one or more Gram-positive bacterial species consists of wavelengths in the range 400-420 nm, and wherein the method is performed outside of the human body and the contact surfaces of the materials are non-living.
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