Crystalline form of a 4-[2-(2-fluorophenoxymethyl)phenyl]piperidine compound
US-10576073-B2 · Mar 3, 2020 · US
US10946007B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10946007-B2 |
| Application number | US-202016903579-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 17, 2020 |
| Priority date | Nov 14, 2008 |
| Publication date | Mar 16, 2021 |
| Grant date | Mar 16, 2021 |
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The invention relates to compounds of formula I: where a, R 1 , and R 3-6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula I are serotonin and norepinephrine reuptake inhibitors. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
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What is claimed is: 1. A compound of the formula: 2. A process for preparing a compound of the formula: the process comprising contacting a compound of the formula: with a compound of the formula: in the presence of potassium carbonate. 3. The process of claim 2 , wherein the process uses a compound of the formula: 4. The process of claim 2 , wherein the process uses a compound of the formula:
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