Composition for food and fat absorption inhibitor

Patent metadata

Field	Value
Publication number	US-10925918-B2
Application number	US-201514601362-A
Country	US
Kind code	B2
Filing date	Jan 21, 2015
Priority date	Sep 25, 2012
Publication date	Feb 23, 2021
Grant date	Feb 23, 2021

Abstract

A composition for food and a fat absorption inhibitor, each including a seaweed polyphenol and a tea extract.

First claim

The invention claimed is:

1. A beneficial bacteria proliferating composition, comprising effective amounts of: a seaweed polyphenol derived from a brown seaweed of the genus Ascophyllum , a green tea extract, and an extract of a plant of the genus Salacia , wherein:
the seaweed polyphenol has a half-maximal (50%) inhibitory concentration (IC 50 value) against lipase of 0.01 μg/ml or lower,
the extract of a plant of the genus Salacia has a half-maximal (50%) inhibitory concentration (IC 50 value) against sucrase of 200 μg/ml or less,
the mass ratio of the green tea extract to the seaweed polyphenol (green tea extract/seaweed polyphenol) is from 15 to 0.05, and
the composition is in a tablet or a capsule, containing an excipient to prevent discoloration.

2. A beneficial bacteria proliferating fat absorption inhibitor comprising effective amounts of: a seaweed polyphenol derived from a brown seaweed of the genus Ascophyllum , a green tea extract, and an extract of a plant of the genus Salacia , wherein:
the seaweed polyphenol has a half-maximal (50%) inhibitory concentration (IC 50 value) against lipase of 0.01 μg/ml or lower,
the extract of a plant of the genus Salacia has a half-maximal (50%) inhibitory concentration of (IC 50 value) against sucrase of 200 μg/ml or less,
the mass ratio of the green tea extract to the seaweed polyphenol (green tea extract/seaweed polyphenol) is from 15 to 0.05, and
the inhibitor is present in a tablet or a capsule, containing an excipient to prevent discoloration.

3. A method of inhibiting fat absorption, the method comprising administering an effective amount of the fat absorption inhibitor according to claim 2 to a subject in need of inhibition of fat absorption.

4. The method of inhibiting fat absorption according to claim 3 , wherein the fat absorption inhibitor further comprises an extract of a plant of the genus Salacia.

5. The method of inhibiting fat absorption according to claim 4 , wherein the extract of a plant of the genus Salacia has a half-maximal (50%) inhibitory concentration (IC 50 value) against sucrase of 2000 μg/ml or less.

6. The method of inhibiting fat absorption according to claim 3 , wherein the seaweed polyphenol is a brown algae-derived polyphenol.

7. The method of inhibiting fat absorption according to claim 3 , wherein the tea extract is a green tea extract.

8. The method of inhibiting fat absorption according to claim 3 , wherein the fat absorption inhibitor is in a tablet form or capsule form.

9. A beneficial intestinal bacteria proliferating composition, comprising effective amounts of: a seaweed polyphenol derived from a brown seaweed of the genus Ascophyllum , a green tea extract, and an extract of a plant of the genus Salacia , wherein:
the seaweed polyphenol has a half-maximal (50%) inhibitory concentration (IC 50 value) against lipase of 0.01 μg/ml or lower,
the extract of a plant of the genus Salacia has a half-maximal (50%) inhibitory concentration (IC 50 value) against sucrase of 200 μg/ml or less,
the mass ratio of the green tea extract to the seaweed polyphenol (green tea extract/seaweed polyphenol) is from 15 to 0.05, and
the composition is in a tablet or a capsule containing an excipient to prevent discoloration.

10. The beneficial intestinal bacteria proliferating composition according to claim 9 , wherein the beneficial intestinal bacteria is bifidobacterium or lactobacillus.

11. A beneficial intestinal bacteria proliferating fat absorption inhibitor, comprising effective amounts of: a seaweed polyphenol derived from a brown seaweed of the genus Ascophyllum , a green tea extract, and an extract of a plant of the genus Salacia , wherein:
the seaweed polyphenol has a half-maximal (50%) inhibitory concentration (IC 50 value) against lipase of 0.01 μg/ml or lower,
the extract of a plant of the genus Salacia has a half-maximal (50%) inhibitory concentration (IC 50 value) against sucrase of 200 μg/ml or less,
the mass ratio of the green tea extract to the seaweed polyphenol (green tea extract/seaweed polyphenol) is from 15 to 0.05, and
the inhibitor is in a tablet or a capsule containing an excipient to prevent discoloration.

12. The beneficial intestinal bacteria proliferating fat absorption inhibitor according to claim 11 , wherein the beneficial intestinal bacteria is bifidobacterium or lactobacillus.

Assignees

• Fujifilm Corp
• FUJIFILM Cornoration

Inventors

• Oda Yuriko
• Ueda Fumitaka

Classifications

• A23L17/60

  Edible seaweed · CPC title

• A23P10/28

  Tabletting; Making food bars by compression of a dry powdered mixture · CPC title

• A23F3/30

  Further treatment of dried tea extract; Preparations produced thereby, e.g. instant tea ({A23F3/166 takes precedence; } flavouring A23F3/40) · CPC title

• A61K36/02

  Algae · CPC title

• A23L33/105

  Plant extracts, their artificial duplicates or their derivatives · CPC title