Implant and method for producing the same

Patent metadata

Field	Value
Publication number	US-10893932-B2
Application number	US-201916358543-A
Country	US
Kind code	B2
Filing date	Mar 19, 2019
Priority date	Apr 23, 2010
Publication date	Jan 19, 2021
Grant date	Jan 19, 2021

Abstract

An implant having a preferably hollow cylindrical basic structure. A nonwoven fabric is disposed in and/or on the basic structure, the nonwoven fabric preferably comprising biocompatible thermoplastic polyurethane and/or a polymer selected from the group consisting of polylactic acid, polycaprolactone, and a copolymer thereof, and/or a polymer including polyphosphazene. At least in at least one section of the implant, preferably at the proximal and/or distal ends of the implant, fastening means are provided or the nonwoven fabric is treated such that, at least in the expanded state of the implant, the protrusion of nonwoven fabric sections from the implant is significantly reduced. Furthermore, a method for producing such an implant is provided.

First claim

What is claimed is:

1. An implant formed as endovascular stent, the implant comprising:
a basic structure formed as a hollow cylinder, wherein the basic structure comprises a magnesium alloy and/or biodegradable polymer;
a nonwoven fabric disposed in and/or on the basic structure, the nonwoven fabric comprising a biocompatible thermoplastic polyurethane and/or a polymer selected from the group consisting of polylactic acid, polycaprolactone, a copolymer of polylactic acid and polycaprolactone, and a polyphosphazene;
wherein at least one section of the implant further comprises a fastening means comprising a hydrogel or a hydrogel-based adhesive or the nonwoven fabric is treated to prevent or reduce, at least in an expanded state of the implant, either:
a protrusion of nonwoven fabric sections from the basic structure, and/or
formation of more extensive regions, which comprises fibers or fiber sections protruding from the basic structure.

2. The implant according to claim 1 , characterized in that the fastening means is disposed on an outside of the nonwoven fabric.

3. The implant according to claim 1 , characterized in that the fastening means comprises an elastic element, optionally an elastic ring.

4. The implant according to claim 1 , characterized in that the nonwoven fabric is produced by way of electrospinning.

5. The implant according to claim 1 , characterized in that treated nonwoven fabric comprises an increased thickness compared to pretreatment.

6. The implant according to claim 1 , characterized in that, the hydrogel forms a bond with a pharmaceutically active substance or facilitates the embedding of such a substance.

7. The implant according to claim 6 , characterized in that, the pharmaceutically active substance is heparin and/or heparansulfate.

8. The implant according to claim 1 , characterized in that, the at least one section of the implant is at a proximal end of the implant.

9. The implant according to claim 1 , characterized in that, the at least one section of the implant is at a distal end of the implant.

Assignees

• Biotronik Ag

Inventors

• Wintsch Daniel
• Loher Stefan
• Quint Bodo
• Bachmann Patrice
• Lang Hans
• Pantic Dragica
• Schwitzer Alwin

Classifications

• A61F2/07 Primary

  Stent-grafts · CPC title

• A61F2002/072

  Encapsulated stents, e.g. wire or whole stent embedded in lining · CPC title

• A61L31/06

  obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds {(A61L31/041 takes precedence)} · CPC title

• Y10T428/24008

  including fastener for attaching to external surface · CPC title

• A61F2250/0063

  Nested prosthetic parts · CPC title