Compounds and compositions for the detection and treatment of alzheimer's disease and related disorders
US-2019381199-A1 · Dec 19, 2019 · US
US10857247B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10857247-B2 |
| Application number | US-201916555290-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 29, 2019 |
| Priority date | Mar 21, 2008 |
| Publication date | Dec 8, 2020 |
| Grant date | Dec 8, 2020 |
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One aspect of the present invention relates to compounds, compositions and methods for diagnosis and/or treatment of a subject suffering from an amyloidosis-associated pathological condition. In certain embodiments, the imaging and/or therapeutic agents of the instant invention may be administered to a subject for identification and/or treatment of amyloid deposits. A specific imaging method detects amyloid deposits by administering the imaging agent to the subject and detecting the spatial distribution of the agent. Differential accumulation of the agent is indicative of AD or an amyloidosis-associated pathological condition and can be monitored by using a PET or SPECT camera.
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We claim: 1. A method for amyloid imaging a subject suffering from Alzheimer's disease comprising the step of: administering a diagnostically effective amount of to the subject.
conjugates with a carrier being an organic compounds · CPC title
Isotopically modified compounds, e.g. labelled · CPC title
containing hydroxy or O-metal groups · CPC title
The ring being saturated · CPC title
containing halogen · CPC title
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