Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders

US10857247B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10857247-B2
Application numberUS-201916555290-A
CountryUS
Kind codeB2
Filing dateAug 29, 2019
Priority dateMar 21, 2008
Publication dateDec 8, 2020
Grant dateDec 8, 2020

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

One aspect of the present invention relates to compounds, compositions and methods for diagnosis and/or treatment of a subject suffering from an amyloidosis-associated pathological condition. In certain embodiments, the imaging and/or therapeutic agents of the instant invention may be administered to a subject for identification and/or treatment of amyloid deposits. A specific imaging method detects amyloid deposits by administering the imaging agent to the subject and detecting the spatial distribution of the agent. Differential accumulation of the agent is indicative of AD or an amyloidosis-associated pathological condition and can be monitored by using a PET or SPECT camera.

First claim

Opening claim text (preview).

We claim: 1. A method for amyloid imaging a subject suffering from Alzheimer's disease comprising the step of: administering a diagnostically effective amount of to the subject.

Assignees

Inventors

Classifications

  • conjugates with a carrier being an organic compounds · CPC title

  • Isotopically modified compounds, e.g. labelled · CPC title

  • C07C43/196Primary

    containing hydroxy or O-metal groups · CPC title

  • The ring being saturated · CPC title

  • containing halogen · CPC title

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What does patent US10857247B2 cover?
One aspect of the present invention relates to compounds, compositions and methods for diagnosis and/or treatment of a subject suffering from an amyloidosis-associated pathological condition. In certain embodiments, the imaging and/or therapeutic agents of the instant invention may be administered to a subject for identification and/or treatment of amyloid deposits. A specific imaging method de…
Who is the assignee on this patent?
Massachusetts Gen Hospital
What technology area does this patent fall under?
Primary CPC classification A61K51/0497. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Dec 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 7 related publications on this page (citations in our corpus or others sharing the same primary CPC).