Polymer

Patent metadata

Field	Value
Publication number	US-10808059-B2
Application number	US-201815993947-A
Country	US
Kind code	B2
Filing date	May 31, 2018
Priority date	Jun 9, 2017
Publication date	Oct 20, 2020
Grant date	Oct 20, 2020

Abstract

To determine and detect 8-oxo-2′-deoxyguanosine in an aqueous sample solution with high sensitivity and specifically, provided is a polymer including a repetition structure represented by any one of the following general formulae 2 to 5, in which a group represented by any one of the following general formulae 6 to 11 is linked to the repetition structure represented by any one of the following general formulae 2 to 5 through a divalent linking group L.

First claim

What is claimed is:

1. A polymer comprising a repetition structure represented by general formula 1:

wherein, in the general formula 1:

is represented by any one of general formulae 2 to 5;

is represented by any one of general formulae 6 to 11; and
L represents a divalent linking group containing 1 to 3 carbon atoms for linking A and B:

wherein, in the general formulae 2 to 5, R 1 to R 4 each independently represents a hydrogen atom or a methyl group, and * represents a bonding position with L, and
wherein, in the general formulae 6 to 11, R 5 to R 27 each independently represents any one of a hydrogen atom, a halogen atom, an alkyl group, an aryl group, a heteroaryl group, an aralkyl group, a hydroxy group, an amino group, a carboxyl group, a sulfo group, and a nitro group, R 5 and R 6 , R 6 and R 7 , R 8 and R 9 , R 9 and R 10 , R 10 and R 11 , R 12 and R 13 , R 13 and R 15 , R 16 and R 17 , R 17 and R 18 , Rig and R 19 , R 20 and R 21 , R 21 and R 22 , R 23 and R 24 , and R 24 and R 27 may each independently be bonded to each other to form a cyclic structure, and ** represents a bonding position with L, and
wherein the polymer comprises a repetition structure represented by general formula 26:

wherein, in the general formula 26:
L 0 represents a divalent group serving as a crosslinked structure together with L 0 of another repetition structure; and

is represented by any one of general formulae 2′ to 5′:

wherein, in the formulae 2′ to 5′, R 1 to R 4 each independently represents a hydrogen atom or a methyl group, and * represents a bonding position with L 0 .

2. The polymer according to claim 1 , wherein, in the general formula 1,

has a cyclic structure.

3. The polymer according to claim 1 , wherein, in the general formula 1,

is represented by any one of general formulae 12 to 17:

wherein, in the general formulae 12 to 17, R 28 to R 54 each independently represents any one of a hydrogen atom, a halogen atom, an alkyl group, an aryl group, a heteroaryl group, an aralkyl group, a hydroxy group, an amino group, a carboxyl group, a sulfo group, and a nitro group, and ** represents a bonding position with L.

4. The polymer according to claim 1 , wherein the polymer comprises any one of repetition structures represented by general formulae 18 to 23:

wherein, in the general formulae 18 to 23, R 1 to R 4 each independently represents a hydrogen atom or a methyl group, and R 28 to R 31 each independently represents any one of a hydrogen atom, a halogen atom, an alkyl group, an aryl group, a heteroaryl group, an aralkyl group, a hydroxy group, an amino group, a carboxyl group, a sulfo group, and a nitro group.

5. The polymer according to claim 1 , further comprising a repetition structure represented by any one of general formulae 32 to 35:

wherein, in the general formulae 32 to 35, R 0 represents any one of a hydrogen atom, an alkyl group, an aryl group, a heteroaryl group, an aralkyl group, and an acyl group, and R 1 to R 4 each independently represents a hydrogen atom or a methyl group.

6. The polymer according to claim 1 , wherein the polymer is obtained by performing a polymerization reaction in a presence of a compound represented by general formula 24:

wherein, in the general formula 24, R 55 represents an alkyl group having 1 to 18 carbon atoms, an aryl group, a heteroaryl group, an aralkyl group, or a structure represented by general formula 25:

wherein, in the general formula 25, R 56 and R 57 each independently represents a hydrogen atom, an alkyl group having 1 to 18 carbon atoms, an aryl group, an acyl group, or a silyl group, and *** represents a bonding position with a nitrogen atom in the general formula 24.

Assignees

• Canon Kk

Inventors

• Tani Yutaka
• Sekiguchi Takeshi
• Mizusawa Keigo
• Higashi Ryuji
• Sugita Masaru
• Kawata Isao

Classifications

• C08F220/603

  and containing oxygen in addition to the carbonamido oxygen and nitrogen · CPC title

• C08F220/36

  containing oxygen in addition to the carboxy oxygen {, e.g. 2-N-morpholinoethyl (meth)acrylate or 2-isocyanatoethyl (meth)acrylate} · CPC title

• C08F220/14

  Methyl esters {, e.g. methyl (meth)acrylate} · CPC title

• C08F220/283

  and containing one or more carboxylic moiety in the chain, e.g. acetoacetoxyethyl(meth)acrylate · CPC title

• C08F220/606

  and containing other heteroatoms · CPC title