Method for improving heart rate estimates by combining multiple measurement modalities

Patent metadata

Field	Value
Publication number	US-10786164-B2
Application number	US-201615346144-A
Country	US
Kind code	B2
Filing date	Nov 8, 2016
Priority date	Dec 12, 2015
Publication date	Sep 29, 2020
Grant date	Sep 29, 2020

Abstract

Systems and methods are provided for determining the frequency of a cardiovascular pulse based on a first physiological signal that is continuously available and a second physiological signal that is less available and that is more accurate or otherwise improved relative to the first signal with respect to pulse rate estimation. When the second signal is available it controls the determination of the pulse rate. When the second signal is unavailable, the first signal is used to determine the pulse rate. This can include using the first signal to estimate the pulse rate until the second signal is available, at which point the pulse rate is estimated based on the second physiological signal. Alternatively, the first signal could be used to determine a number of candidate pulse rates, and the second signal could be used to select a pulse rate from the set of candidate pulse rates.

First claim

What is claimed is:

1. A method comprising:
detecting, via a first sensor, a first signal related to a cardiovascular pulse;
sampling the first signal during a first period of time to obtain a first set of samples of the first signal;
determining a pulse rate for the first period of time based on the first set of samples of the first signal;
sampling the first signal during a second period of time to obtain a second set of samples of the first signal, wherein the first period of time precedes the second period of time;
determining that a second signal related to the cardiovascular pulse is being detected, during the second period of time, via a second sensor;
responsive to determining that the second signal related to the cardiovascular pulse is being detected during the second period of time via the second sensor: (1) determining a second-signal pulse rate based on the second signal; (2) determining a pulse rate for the second period of time based on (i) the second set of samples of the first signal and (ii) the second-signal pulse rate; and (3) providing, via a user interface, an indication of the pulse rate for the second period of time;
updating the pulse rate for the first period of time based on the determined pulse rate for the second period of time; and
providing, via the user interface, an indication of the updated pulse rate for the first period of time.

2. The method of claim 1 , wherein determining a pulse rate for the second period of time based on (i) the second set of samples of the first signal and (ii) the second-signal pulse rate comprises:
determining a plurality of potential pulse rates based on the second set of samples of the first signal; and
selecting one of the potential pulse rates as the pulse rate for the second period of time.

3. The method of claim 2 , wherein selecting one of the potential pulse rates as the pulse rate for the second period of time comprises:
for each potential pulse rate, determining a respective difference between the potential pulse rate and the second-signal pulse rate; and
selecting the potential pulse rate that has the smallest difference as the pulse rate for the second period of time.

4. The method of claim 1 , wherein determining a pulse rate for the second period of time based on the second set of samples of the first signal comprises:
determining first spectral content of the first signal during the second period of time based on the second set of samples of the first signal; and
determining a pulse rate for the second period of time based on the determined first spectral content and the second-signal pulse rate.

5. The method of claim 1 , wherein determining that a second signal related to the cardiovascular pulse is being detected via a second sensor comprises:
detecting, via the second sensor, the second signal;
sampling the second signal to obtain a set of samples of the second signal; and
determining, based on the set of samples of the second signal, whether a pulse rate can be reliably determined from the set of samples of the second signal.

6. The method of claim 1 , wherein the second signal comprises an electrocardiographic signal.

7. The method of claim 6 , wherein detecting the second signal via the second sensor comprises extracting an electrocardiographic signal from voltage fluctuations between a first electrical contact and a second electrical contact of a body-mountable device, wherein the body-mountable device comprises:
a housing that is mountable to a first external body surface, wherein the first external body surface is a wrist location of a first arm of a wearer;
the first electrical contact, wherein the first electrical contact is disposed on the housing, wherein the first electrical contact contacts skin at the first external body surface when the housing is mounted on the first external body surface; and
the second electrical contact, wherein the second electrical contact is configured to be contacted by skin of a second external body surface, wherein the second external body surface is a location of a second arm of the wearer.

8. The method of claim 1 wherein detecting the first signal related to a cardiovascular pulse comprises:
illuminating a portion of subsurface vasculature; and
receiving light emitted from the portion of subsurface vasculature in response to illumination, wherein sampling the first signal to obtain samples of the first signal comprises measuring the received light at a plurality of points in time.

9. A system comprising:
a first sensor;
a second sensor;
a user interface; and
a controller operably coupled to the first sensor and the second sensor, wherein the controller comprises a computing device programmed to perform controller operations comprising:
operating the first sensor to detect a first signal, wherein the first signal is related to a cardiovascular pulse;
sampling the first signal during a first period of time to obtain a first set of samples of the first signal;
determining a pulse rate for the first period of time based on the first set of samples of the first signal;
sampling the first signal during a second period of time to obtain a second set of samples of the first signal, wherein the first period of time precedes the second period of time;
operating the second sensor to detect a second signal during the second period of time;
determining whether the detected second signal is related to the cardiovascular pulse and, if it is determined that the detected second signal is related to the cardiovascular pulse, determining a second-signal pulse rate;
determining a pulse rate for the second period of time based on (i) the second set of samples of the first signal and, if it is determined that the detected second signal is related to the cardiovascular pulse, (ii) the second-signal pulse rate;
updating the pulse rate for the first period of time based on the pulse rate for the second period of time; and
providing, via the user interface, an indication of the updated pulse rate for the first period of time.

10. The system of claim 9 , wherein the first sensor comprises:
a light emitter; and
a light detector, wherein operating the first sensor to detect the first signal comprises: (a) operating the light emitter to illuminate a portion of subsurface vasculature and (b) operating the light detector to detect light emitted from the portion of subsurface vasculature in response to illumination, wherein sampling the first signal to obtain samples of the first signal comprises measuring the received light at a plurality of points in time.

11. The system of claim 9 , wherein the system comprises a body-mountable device.

12. The system of claim 9 , wherein determining whether the detected second signal is related to the cardiovascular pulse comprises:
sampling the second signal to obtain a set of samples of the second signal; and
determining, based on the set of samples of the second signal, whether a pulse rate can be reliably determined from the set of samples of the second signal.

13. The system of claim 9 , wherein the second signal comprises an electrocardiographic signal.

14. The system of claim 13 , further comprising:
a housing that is mountable to a first external body surface, wherein the first external body surface is a wrist location of a first arm of a wearer;
a first electrical contact disposed on the housing, wherein the first electrical contact contacts skin at the first external body surface when the housing is mounted on the first external body surface;
a second electrical contact, wherein the second electrical contact is configured to be contacted b

Assignees

• Verily Life Sciences Llc

Inventors

• Murphy Mark
• Mirov Russell Norman
• Lengerich Christopher Towles

Classifications

• A61B5/721

  using a separate sensor to detect motion or using motion information derived from signals other than the physiological signal to be measured · CPC title

• A61B5/7221

  Determining signal validity, reliability or quality (preventing, reducing or removing noise induced by motion artefacts A61B5/7207; noise originating from a therapeutic or surgical apparatus A61B5/7217) · CPC title

• G04G21/025

  for measuring physiological data · CPC title

• A61B5/0245

  by using sensing means generating electric signals, {i.e. ECG signals} · CPC title

• A61B5/681

  Wristwatch-type devices · CPC title