System and method for extracting ethanol from a fermentation broth

Patent metadata

Field	Value
Publication number	US-10752875-B2
Application number	US-201515325557-A
Country	US
Kind code	B2
Filing date	Jul 10, 2015
Priority date	Jul 11, 2014
Publication date	Aug 25, 2020
Grant date	Aug 25, 2020

Abstract

The present invention is directed to a system and method for producing an organic compound using fermentation wherein multiple components of the system are recycled within the system. The system and method allow for extraction of a high concentration of the organic compound from the fermentation broth in a continuous system that allows recycling of the biomass, aqueous fermentation broth and extraction solvents. The system and method are particularly well adapted for producing and extracting ethanol.

First claim

The invention claimed is:

1. A system for production of an organic compound from a sugar source by fermentation, comprising:
a fermentation vessel for containing a fermentation broth;
a solids separation means in fluid connection with the fermentation vessel to receive at least a portion of the fermentation broth,
wherein said solids separation means is configured to separate suspended solids from the fermentation broth to produce a clarified broth, and
wherein said solids separation means is configured to conduct a flow of the clarified broth out of the separation means;
a membrane module configured to receive the flow of clarified broth, wherein said membrane module comprises a selectively permeable membrane configured to permit passage of the organic compound relative to water and wherein said membrane module comprises:
a broth inlet port to receive the flow of clarified broth from the solids separation means in a first flow direction tangential to the selectively permeable membrane;
a broth exit port to conduct a flow of solvent-extracted broth comprising residual extraction solvent from the membrane module;
a solvent inlet port to receive a flow of an extraction solvent in a second flow direction, wherein the second flow direction is countercurrent or crosscurrent to the first flow direction;
an outlet port configured to conduct the flow of extraction solvent containing the organic compound from the membrane module; and
a pressurizing means to maintain a positive pressure on the flow of clarified broth relative to the flow of extraction solvent in the membrane module;
a decanter configured to receive the flow of solvent-extracted broth from the membrane module and to separate an extraction solvent phase comprising a portion of said residual extraction solvent from an aqueous phase of the solvent-extracted broth; and
a separation enhancing means operably connected to the decanter and configured to slow a rate of the flow of solvent-extracted broth and thereby enhance separation of the extraction solvent phase from the aqueous phase.

2. The system of claim 1 , wherein said solids separation means comprises at least one filtration apparatus.

3. The system of claim 2 , wherein said at least one filtration apparatus comprises a plurality of the filtration apparatuses.

4. The system of claim 2 , wherein said at least one filtration apparatus is configured with a means to return at least a portion of the separated suspended solids to the fermentation vessel.

5. The system of claim 1 , wherein said suspended solids comprise a residual amount of the fermentation broth and wherein said solids separation means is configured with a means to separate the suspended solids from the residual fermentation broth and return the residual fermentation broth to the fermentation vessel.

6. The system of claim 1 , wherein said pressurizing means comprises a vent for releasing carbon dioxide contained in the clarified broth from the membrane module.

7. The system of claim 1 , further comprising a pump operably connected to the membrane module to increase a rate of flow of the extraction solvent within said module relative to a rate of the flow of the extraction solvent into and out of said membrane module.

8. The system of claim 1 , further including a distillation apparatus configured to receive the flow of extraction solvent from the membrane module and to separate the extraction solvent from the organic compound by distillation.

9. The system of claim 8 , wherein said system is further configured to return the distilled solvent from the distillation apparatus to the flow of extraction solvent into the membrane module.

10. The system of claim 1 , further comprising a liquid/liquid extraction module in fluid communication with the decanter, configured to receive the solvent-extracted broth and to contact the solvent-extracted broth with a second extraction solvent.

11. The system of claim 1 , wherein the organic compound is ethanol.

12. The system of claim 10 , wherein the second extraction solvent comprises dodecane.

13. A method of making an organic compound by fermentation, comprising fermenting a carbohydrate source with a fermentation organism that makes the organic compound in a system according to claim 1 ; and
collecting the organic compound.

14. The method claim 13 , wherein the organic compound is ethanol.

15. The system of claim 1 , wherein the extraction solvent comprises a solvent selected from the group consisting of dodecane and 2, 4-dimethylheptanol.

16. The system of claim 1 , where said fermentation vessel comprises:
a first fermenter inlet port for receiving a flow of carbohydrate feed stock into the fermentation vessel; a second fermenter inlet port for receiving the flow of the solvent extracted broth into the fermentation vessel; and
a fermenter exit port configured to conduct a portion of the fermentation broth from the fermentation vessel to the solids separation means.

17. The system of claim 16 , wherein the fermentation vessel further includes a third fermenter inlet port configured for receiving the separated suspended solids.

Assignees

• Archer Daniels Midland Co
• Archer-Daniels-Midland Company

Inventors

• Abbas Charles A
• Brown Dan L
• Dyer Matt
• Isder Mark D
• Nelson Travis
• Fanselow Dan L
• Fitzsimons Robert T
• Nakamura Masayuki
• Reed John F
• Bone Brian
• Sammons Rhea J
• Barnes Jerry
• Fults Jerod

Classifications

• Y02E50/10

  Biofuels, e.g. bio-diesel · CPC title

• C12P7/14

  Multiple stages of fermentation; Multiple types of microorganisms or re-use of microorganisms · CPC title

• C12P7/06 Primary

  Ethanol, i.e. non-beverage · CPC title

• C12M29/18

  External loop; Means for reintroduction of fermented biomass or liquid percolate (loop type reactors for chemical or physical processes B01J19/2435) · CPC title

• C12M47/12

  Purification (C12M47/04 takes precedence) · CPC title