Oxysterols and methods of use thereof
US-10259840-B2 · Apr 16, 2019 · US
Oxysterols and methods of use thereof
US10723758B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10723758-B2 |
| Application number | US-201816028790-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 6, 2018 |
| Priority date | Jun 18, 2014 |
| Publication date | Jul 28, 2020 |
| Grant date | Jul 28, 2020 |
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- Title
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Abstract
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Compounds are provided according to Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein X, Y, R 1 , R 2a , R 2b , R 4a , R 4b , R 5a , R 5b , R 6a , R 6b , R 7 , and R 8 are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of inducing sedation or anesthesia, comprising administering to a subject an effective amount of a compound having the following structure: or a pharmaceutically acceptable salt thereof. 2. A method for modulating an NMDA receptor in a subject having a CNS-related condition, comprising administering to the subject an effective amount of a compound having the following structure: or a pharmaceutically acceptable salt thereof, wherein the CNS-related condition is obsessive-compulsive disorder, posttraumatic stress disorder, social phobia, Alzheimer's disease and other forms of dementia, eating disorder, schizophrenia, autism spectrum disorders, pain, anti-NMDA receptor encephalitis, Huntington's disease, or Parkinson's disease.
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Classifications
containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton · CPC title
not covered by C07J31/003 · CPC title
Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches (A61K9/0007 takes precedence; eatable gels or foams A61K9/0056; oral mucosa adhesive forms A61K9/006) · CPC title
Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner (non-active ingredients are additionally classified in A61K47/00) · CPC title
Ophthalmic agents · CPC title
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- What does patent US10723758B2 cover?
- Compounds are provided according to Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein X, Y, R 1 , R 2a , R 2b , R 4a , R 4b , R 5a , R 5b , R 6a , R 6b , R 7 , and R 8 are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.
- Who is the assignee on this patent?
- Sage Therapeutics Inc
- What technology area does this patent fall under?
- Primary CPC classification C07J9/00. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jul 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 7 related publications on this page (citations in our corpus or others sharing the same primary CPC).