Neuroactive steroids and methods of use thereof
US-2016031930-A1 · Feb 4, 2016 · US
US10227375B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10227375-B2 |
| Application number | US-201815917263-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 9, 2018 |
| Priority date | Mar 13, 2013 |
| Publication date | Mar 12, 2019 |
| Grant date | Mar 12, 2019 |
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Compounds are provided according to Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein R 1 , R 2 , R 3a , R 3b , R 4 , R 5a , R 5b , R 6a , and R 6b are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of CNS-related conditions.
Opening claim text (preview).
The invention claimed is: 1. A compound of the structure: where the absolute stereochemistry of the compound is as shown. 2. A pharmaceutically acceptable salt of a compound, wherein the compound is of the structure where the absolute stereochemistry of the compound is as shown. 3. A pharmaceutical composition comprising a compound according to claim 1 and a pharmaceutically acceptable excipient. 4. A pharmaceutical composition comprising a pharmaceutically acceptable salt according to claim 2 and a pharmaceutically acceptable excipient.
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