Biaryl kinase inhibitors

US10723734B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10723734-B2
Application numberUS-201916443929-A
CountryUS
Kind codeB2
Filing dateJun 18, 2019
Priority dateApr 2, 2014
Publication dateJul 28, 2020
Grant dateJul 28, 2020

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

    Technology tags used to group this patent with similar filings.

  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method for treating or managing a disease or a disorder mediated by AAK1 activity, the method comprising administering to a patient in need thereof a therapeutically effective amount of (S)-1-((2′,6-bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine, or a pharmaceutically acceptable salt thereof, wherein a disease or disorder mediated by AAKI activity is Alzheimer's disease.

Assignees

Inventors

Classifications

  • C07D471/04Primary

    Ortho-condensed systems · CPC title

  • directly linked by a ring-member-to-ring-member bond · CPC title

  • containing only hydrogen and carbon atoms in addition to the ring hetero atom · CPC title

  • with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms · CPC title

  • C07D213/74Primary

    Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals · CPC title

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Frequently asked questions

Answers are generated from the same data shown on this page.

What does patent US10723734B2 cover?
The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.
Who is the assignee on this patent?
Bristol Myers Squibb Co
What technology area does this patent fall under?
Primary CPC classification C07D471/04. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jul 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 5 related publications on this page (citations in our corpus or others sharing the same primary CPC).