Powder, method of producing powder, and adsorption apparatus

Patent metadata

Field	Value
Publication number	US-10710050-B2
Application number	US-201615281665-A
Country	US
Kind code	B2
Filing date	Sep 30, 2016
Priority date	Sep 28, 2009
Publication date	Jul 14, 2020
Grant date	Jul 14, 2020

Abstract

The present invention provides that powder is mainly constituted from secondary particles of hydroxyapatite. The secondary particles are obtained by drying a slurry containing primary particles of hydroxyapatite and aggregates thereof and granulating the primary particles and the aggregates. A bulk density of the powder is 0.65 g/mL or more and a specific surface area of the secondary particles is 70 m 2 /g or more. The powder of the present invention has high strength and is capable of exhibiting superior adsorption capability when it is used for an adsorbent an adsorption apparatus has.

First claim

What is claimed is:

1. A method of producing sintered powder including sintered secondary particles mainly formed of hydroxyapatite, the method comprising:
mixing a first liquid containing a calcium source to be a raw material of the hydroxyapatite with a second liquid containing a phosphoric source to be the raw material of the hydroxyapatite to obtain a mixture;
reacting the calcium source with the phosphoric source with stirring of the mixture to obtain a slurry containing primary particles of the hydroxyapatite and aggregates thereof;
physically crushing the aggregates contained in the slurry to disperse the crushed aggregates in the slurry;
granulating the primary particles and the crushed aggregates by spraying and drying the slurry to obtain secondary particles; and
sintering the secondary particles at a sintering temperature to obtain the sintered powder,
wherein the physically crushing of the aggregates is performed by a wet-type jet mill method in which the slurry is sprayed under a high pressure to obtain droplets of the slurry and the droplets are crashed to each other, and
wherein a compressive particle strength of the sintered secondary particles is obtained by the wet-type jet milling and sintering is over 7.0 MPa.

2. The method as claimed in claim 1 , wherein power for stirring the mixture is in the range of 0.75 W to 2.0 W per 1 L of the mixture.

3. The method as claimed in claim 1 , wherein a content of the calcium source in the first liquid is in the range of 5 wt % to 15 wt % and a content of the phosphoric source in the second liquid is in the range of 10 wt % to 25 wt %.

4. The method as claimed in claim 1 , wherein the mixing the first liquid with the second liquid is performed by dropping the second liquid into the first liquid at a rate of 1 L/hour to 40 L/hour.

5. The method as claimed in claim 4 , wherein a time for dropping the second liquid into the first liquid is in the range of 5 hours to 32 hours.

6. The method as claimed in claim 1 , wherein the physically crushing the aggregates is performed such that an average particle size of the crushed aggregates is 1 μm or less.

7. The method as claimed in claim 1 , wherein the physically crushing the aggregates is performed such that an average particle size of the crushed aggregates is in the range of 0.1 μm to 0.74 μm.

8. The method as claimed in claim 1 , wherein an average particle size of the secondary particles is in the range of 2 μm to 100 μm.

9. The method as claimed in claim 1 , wherein an average particle size of the secondary particles is in the range of 3 μm to 10 μm.

10. The method as claimed in claim 1 , wherein a bulk density of the sintered powder is 0.65 g/mL or more and a specific surface area of the sintered secondary particles is in the range of 25 to 52 m 2 /g.

11. The method as claimed in claim 1 , wherein the sintering temperature is in the range of about 200° C. to 900° C.

12. The method as claimed in claim 1 , wherein the sintering temperature is in the range of about 400° C. to 700° C.

13. The method as claimed in claim 1 , wherein a compressive particle strength of the sintered secondary particles is obtained by the wet-type jet milling and sintering is over 9.0 MPa.

14. The method as claimed in claim 13 , wherein the sintering temperature is in the range of about 400° C. to 700° C.

15. The method as claimed in claim 1 wherein the secondary particles are classified so as to have an average particle size of 40±4 μm.

16. The method as claimed in claim 14 wherein the secondary particles are classified so as to have an average particle size of 40±4 μm, and the classified secondary particles are sintered.

17. The method as claimed in claim 1 wherein in the case where under the conditions that the secondary particles are classified so as to have an average particle size of 40±4 μm, and the classified secondary particles are sintered at a temperature of 700° C., a compressive particle strength of the classified and sintered secondary particles is measured, which is over 9.0 MPa, or wherein in the case where under the conditions that the secondary particles are classified so as to have an average particle size of 40±4 μm, and the classified secondary particles are sintered at a temperature of 400° C., a compressive particle strength of the classified and sintered secondary particles is measured, which is over 7.0 MPa.

18. The method as claimed in claim 17 , wherein the sintering temperature is in the range of about 200° C. to 900° C.

Assignees

• Hoya Corp

Inventors

• Kobayashi Shintaro

Classifications

• G01N30/88

  Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 · CPC title

• C01B25/327

  After-treatment · CPC title

• B01J20/28011

  Other properties, e.g. density, crush strength · CPC title

• B01J2220/52

  Sorbents specially adapted for preparative chromatography · CPC title

• B01J20/28016

  Particle form · CPC title