Composition for inhibition of insect host sensing

Patent metadata

Field	Value
Publication number	US-10701938-B2
Application number	US-201816145996-A
Country	US
Kind code	B2
Filing date	Sep 28, 2018
Priority date	Oct 25, 2010
Publication date	Jul 7, 2020
Grant date	Jul 7, 2020

Abstract

The present invention provide chemical modulators of insect olfactory receptors. In particular, compounds and compositions are provided that can inhibit host targeting functions in insects such as mosquitos. Method of employing such agents, and articles incorporating the same, are also provided.

First claim

What is claimed is:

1. A method of disrupting odor-sensing behavior in an organism having an ORco ion channel, comprising exposing the organism to a compound:

or a salt thereof.

2. The method of claim 1 , wherein the organism is an insect.

3. The method of claim 1 , wherein the organism is a crop pest.

4. The method of claim 1 , wherein the organism is an airborne insect.

5. The method of claim 1 , wherein the organism is a blood-sucking insect.

6. The method of claim 1 , wherein the organism is of the suborder Ixodida.

7. The method of claim 1 , wherein the organism is of the order Diptera.

8. The method of claim 1 , wherein the organism is of the order Lepidoptera.

9. A method of disrupting odor-sensing behavior in an insect, comprising exposing the insect to a compound:

or a salt thereof.

10. The method of claim 9 , wherein the insect is a mosquito.

11. The method of claim 9 , wherein the insect is a crop pest.

12. The method of claim 9 , wherein the insect is an airborne insect.

13. The method of claim 9 , wherein the insect is a blood-sucking insect.

14. The method of claim 9 , wherein the insect is of the suborder Ixodida.

15. The method of claim 9 , wherein the insect is of the order Diptera.

16. The method of claim 9 , wherein the insect is of the order Lepidoptera.

Assignees

• Univ Vanderbilt

Inventors

• Zwiebel Laurence
• Pask Gregory M
• Rinker David
• Jones Patrick L

Classifications

• A01N25/12

  Powders or granules (A01N25/26 takes precedence) · CPC title

• A01M1/2016

  for flying insects · CPC title

• A01M7/0003

  Atomisers or mist blowers (single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use B05B11/00) · CPC title

• A01M2200/012

  Flying insects · CPC title

• A01N61/00

  Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action · CPC title