Oral care composition containing zinc salts and calcium carbonate

Patent metadata

Field	Value
Publication number	US-10646422-B2
Application number	US-201916284498-A
Country	US
Kind code	B2
Filing date	Feb 25, 2019
Priority date	Nov 14, 2014
Publication date	May 12, 2020
Grant date	May 12, 2020

Abstract

The present invention provides an oral care composition comprising: (a) a first composition comprising a silica abrasive and a first zinc compound selected from zinc citrate, zinc chloride, zinc acetate, zinc lactate, zinc salicylate, zinc sulfate, and zinc nitrate; and (b) a second composition comprising a calcium carbonate abrasive; wherein the first composition and/or the second composition further comprises a second zinc compound selected from zinc oxide, zinc carbonate and zinc tartrate; and wherein the oral care composition optionally further comprises from 0.1 to 1.75 weight % of a tartar control agent, based on the total weight of the oral care composition.

First claim

What is claimed is:

1. An oral care composition comprising:
(a) a first composition comprising a silica abrasive and a first zinc compound wherein the first zinc compound is zinc citrate; and
(b) a second composition comprising a calcium carbonate abrasive and a second zinc compound, wherein the second zinc compound is zinc oxide;
wherein the weight ratio of the second zinc compound to the first zinc compound in the oral care composition is from 1.5:1 to 4.5:1.

2. The oral care composition of claim 1 , wherein the oral care composition further comprises from 0.1 to 1.75 weight % of a tartar control agent, based on the total weight of the oral care composition.

3. The oral care composition of claim 1 , wherein the concentration of the first zinc compound in the oral care composition is from 0.25 to 0.75 weight %, based on the total weight of the oral care composition.

4. The oral care composition of claim 1 , wherein the concentration of the second zinc compound in the oral care composition is from 0.5 to 1.5 weight %, based on the total weight of the oral care composition.

5. The oral care composition of claim 1 , wherein the concentration of the silica abrasive in the oral care composition is from 1 to 10 weight %, based on the total weight of the composition.

6. The oral care composition of claim 1 , wherein the concentration of the calcium carbonate abrasive in the oral care composition is from 20 to 40 weight %, based on the total weight of the composition.

7. The oral care composition of claim 1 wherein the first composition is a toothpaste.

8. The oral care composition of claim 1 wherein the first composition is a gel.

9. The oral care composition of claim 1 wherein the second composition is a toothpaste.

10. The oral care composition of claim 1 , wherein the weight ratio of the first composition to the second composition is from 1:8 to 1:1.

11. The oral care composition of claim 1 , wherein the oral care composition is a striped dentifrice comprising a main dentifrice material and a stripe dentifrice material, the first composition being the stripe dentifrice material and the second composition being the main dentifrice material.

12. The oral care composition of claim 2 , wherein the tartar control agent is a monobasic, dibasic or tribasic sodium phosphate; a mono-, di- or trisodium pyrophosphate; a mono-, di- or tripotassium pyrophosphate; tetrasodium pyrophosphate (TSPP); tetrapotassium pyrophosphate (TKPP); sodium or potassium tripolyphosphate; sodium or potassium tetrapolyphosphate; sodium or potassium trimetaphosphate; sodium or potassium hexametaphosphate; or a combination of any two or more thereof.

13. The oral care composition according to claim 1 , wherein the composition comprises a fluoride source.

14. The oral care composition according to claim 13 , wherein the fluoride source is at least one selected from stannous fluoride, sodium fluoride, potassium fluoride, sodium monofluorophosphate, sodium fluorosilicate, ammonium fluorosilicate, amine fluoride, and ammonium fluoride.

15. A method of reducing or inhibiting biofilm formation in an oral cavity, the method comprising contacting the oral cavity with an oral care composition according to claim 1 .

16. A method of enhancing the antibacterial efficacy of an oral care composition comprising a calcium carbonate abrasive and at least one zinc salt, the method comprising providing the oral care composition according to claim 1 as an oral care composition.

17. A method of forming an oral care composition, comprising adding
(a) a first composition comprising a silica abrasive and a first zinc compound, wherein the first zinc compound is zinc citrate; to
(b) a second composition comprising a calcium carbonate abrasive;
wherein the second composition further comprises zinc oxide;
and wherein the concentration of the first zinc compound in the second composition is less than 0.01 weight %, based on the weight of the second composition.

Assignees

• Colgate Palmolive Co

Inventors

• Subramanyam Ravi
• Jogun Suzanne
• Hassan Mahmoud
• Lewis Navin
• Huang Xiao Yi
• Xu Shao Peng

Classifications

• A61K8/21

  Fluorides; Derivatives thereof · CPC title

• A61Q11/00

  Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title

• A61K8/19

  containing inorganic ingredients · CPC title

• A61K8/25

  Silicon; Compounds thereof · CPC title

• A61K8/042

  Gels · CPC title