Two-Phase Dentifrices

Patent metadata

Field	Value
Publication number	US-2016000667-A1
Application number	US-201314770901-A
Country	US
Kind code	A1
Filing date	Mar 19, 2013
Priority date	Mar 19, 2013
Publication date	Jan 7, 2016
Grant date	—

Abstract

Described herein are toothpastes comprising a first dentifrice comprising a calcium carbonate abrasive and a second dentifrice comprising a zinc ion source in a gel base, wherein the second dentifrice is entrained as a stripe in the first dentifrice, as well as products comprising the toothpaste and methods of making and using the same.

First claim

We claim:

1 . A toothpaste product comprising
a first dentifrice comprising a calcium carbonate abrasive, a second dentifrice comprising a zinc ion source in a gel base, and a container which holds the first dentifrice physically separate from the second dentifrice until the dentifrices are dispensed.

2 . The product of claim 1 , wherein the product is capable of dispensing the second dentifrice as a stripe entrained in the first dentifrice.

3 . The toothpaste product of claim 1 , wherein the zinc ion source is selected from zinc oxide, zinc citrate, and mixtures thereof.

4 . The toothpaste product of claim 1 , wherein the amount of first dentifrice relative to the second dentifrice is from 3:1 to 5:1.

5 . The toothpaste product of claim 1 wherein the second dentifrice contains zinc in an amount of 0.1 to 10% by weight of the second dentifrice.

6 . The toothpaste product of claim 1 wherein the second dentifrice contains a zinc ion source selected from (i) zinc oxide in an amount of 0.1 to 6%; (ii) zinc citrate in an amount of 0.1 to 10%; and (iii) zinc oxide in an amount of 0.1 to 6% and zinc citrate in an amount of 0.1 to 10%.

7 . The toothpaste product of claim 1 wherein the ratio of the first dentifrice to the second dentifrice is about 4:1 and the second dentifrice contains about 5% zinc oxide.

8 . The toothpaste product of claim 1 wherein the second dentifrice comprises a viscosity-modifying amount of one or more thickening agents selected from carboxymethyl cellulose, xanthan, thickening silica, and mixtures thereof.

9 . The toothpaste product of claim 1 wherein the calcium carbonate abrasive in the first dentifrice is a mixture of precipitated calcium carbonate and natural calcium carbonate in an amount of 35-45% by weight of the first dentifrice.

10 . The toothpaste product of claim 1 wherein the second dentifrice comprises silica abrasive in an amount of 10-40% by weight of the second dentifrice.

11 . The toothpaste product of claim 1 wherein the first dentifrice is an opaque white paste and the second abrasive is a colored translucent gel.

12 . A striped toothpaste comprising a first dentifrice comprising a calcium carbonate abrasive, second dentifrice comprising a zinc ion source and a silica gel portion, wherein the second dentifrice is entrained as a stripe in the first dentifrice, and wherein the zinc ion source is concentrated in the silica gel portion.

13 . A method of making a dentifrice comprising a first dentifrice comprising a calcium carbonate abrasive and a second dentifrice comprising a zinc ion source and a silica gel portion, comprising entraining the second dentifrice as a stripe in the first dentifrice, and wherein the zinc ion source is concentrated in the silica gel portion.

14 . A method of treating or preventing a condition of the oral cavity, comprising administering a composition according to claim 1 , to the oral cavity of a subject in need thereof.

15 . (canceled)

16 . (canceled)

Assignees

• Potnis Shashank
• Ramanyam Ravi
• Lewis Navin
• Colgate Palmolive Co

Inventors

• Potnis Shashank
• Subramanyam Ravi
• Lewis Navin

Classifications

• A61K8/25

  Silicon; Compounds thereof · CPC title

• A61Q11/00

  Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title

• A61K8/19

  containing inorganic ingredients · CPC title

• A61K2800/262

  Transparent; Translucent · CPC title

• A61K2800/5922

  At least two compounds being classified in the same subclass of A61K8/18 · CPC title