Modulators of sphingosine phosphate receptors
US-9975863-B2 · May 22, 2018 · US
US10544136B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10544136-B2 |
| Application number | US-201815959935-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 23, 2018 |
| Priority date | May 14, 2008 |
| Publication date | Jan 28, 2020 |
| Grant date | Jan 28, 2020 |
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Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided.
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What is claimed is: 1. A compound that is any of: or any pharmaceutically acceptable salt, tautomer, stereoisomer, solvate, hydrate, or prodrug thereof.
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