Method for producing antibiotic from pleosporaceae ulocladium

US10508095B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10508095-B2
Application numberUS-201815885869-A
CountryUS
Kind codeB2
Filing dateFeb 1, 2018
Priority dateJan 27, 2017
Publication dateDec 17, 2019
Grant dateDec 17, 2019

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  1. Title

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  2. Abstract

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  5. First independent claim

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Abstract

Official abstract text for this publication.

Fermentation processes that use fungi of the genus Ulocladium for producing novel compounds that include an 8- or 9-membered cyclic structure, wherein an (E)-1,4-dioxo-but-2-ene moiety is embedded in the cyclic structure. The compounds may be used as medicaments, in particular as medicaments for treating and preventing microbial infections, such as infections by multidrug resistant and/or Gram-positive bacteria.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method for producing a compound comprising an (E)-7-hydroxy-4-oxo-hept-2-enoic acid lactone ring, the method comprising: (a) culturing a fungus of the fungal Family of Pleosporaceae of the genus Ulocladium , in a medium conducive to the production of the compound; and, (b) optionally recovery of the compound. 2. The method according to claim 1 , wherein the culturing is at a temperature less than 30° C. 3. The method according to claim 1 , wherein the compound is recovered by solvent extraction. 4. The method according to claim 3 , wherein the solvent is ethyl acetate.

Assignees

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Classifications

  • C07D313/18Primary

    not condensed with other rings · CPC title

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What does patent US10508095B2 cover?
Fermentation processes that use fungi of the genus Ulocladium for producing novel compounds that include an 8- or 9-membered cyclic structure, wherein an (E)-1,4-dioxo-but-2-ene moiety is embedded in the cyclic structure. The compounds may be used as medicaments, in particular as medicaments for treating and preventing microbial infections, such as infections by multidrug resistant and/or Gram-…
Who is the assignee on this patent?
Koninklijke Nederlandse Akademie Van Wetenschappen
What technology area does this patent fall under?
Primary CPC classification C07D313/18. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Dec 17 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).