System and method for receiving a single-use vessel

Patent metadata

Field	Value
Publication number	US-10500554-B2
Application number	US-201815904969-A
Country	US
Kind code	B2
Filing date	Feb 26, 2018
Priority date	Jan 29, 2016
Publication date	Dec 10, 2019
Grant date	Dec 10, 2019

Abstract

A system for receiving a single-use vessel containing a mixing device has a support structure adapted to receive the single-use vessel and a drive-unit adapted to power, to control, or to power and control a mixing of contents of the single-use vessel when the single-use vessel is arranged in the support structure. The support structure and the drive-unit are provided as separate components that may be arranged both in an operating position, where the drive-unit is connectable to the mixing device of the single-use bag in the support structure, and in a separated position, where the drive-unit is separated from the support structure. The drive-unit comprises a tag reader that, in the operating position, is arranged to read a vessel tag of the single-use vessel arranged in the support structure.

First claim

What is claimed is:

1. A single-use bioreactor vessel for mixing media therein, the single use bioreactor vessel comprising:
a flexible bag having at least one flexible wall defining an enclosure for the media to be mixed;
at least one sensor mounted in the flexible wall; and
a vessel tag at a position facing substantially outwards, the vessel tag carrying readable information identifying the flexible bag and identifying the at least one sensor,
wherein the single-use bioreactor vessel is configured to be received by a support structure of a system such that the vessel tag is arranged to be read by a tag reader of the system so that the tag reader reads the readable information identifying the flexible bag and identifying the at least one sensor.

2. The single-use bioreactor vessel of claim 1 , wherein the flexible bag is made of a flexible multilayer film.

3. The single-use bioreactor vessel of claim 1 , further comprising a mixing device at a bottom side of the flexible bag, the mixing device being configured to be connected to an external motor for powering the mixing device.

4. The single-use bioreactor vessel of claim 3 , wherein the vessel tag is arranged at a predetermined position relative to the mixing device.

5. The single-use bioreactor vessel of claim 1 , wherein the readable information carried by the vessel tag and identifying the flexible bag comprises at least one of:
a product code,
a product type,
a serial number,
a lot number,
a flexible bag volume,
manufacturing date,
irradiation date,
expiration dates, and
manufacturer test results.

6. The single-use bioreactor vessel of claim 3 , wherein the mixing device comprises an impeller arranged within the flexible bag, the readable information carried by the vessel tag and identifying the flexible bag comprises information identifying the mixing impeller.

7. The single-use bioreactor vessel of claim 1 , wherein the vessel tag is a 2D bar code.

8. The single-use bioreactor vessel of claim 1 , wherein the vessel tag is an RFID tag.

9. The single-use bioreactor vessel of claim 1 , wherein the flexible bag further comprises a powder port and wherein the readable information carried by the vessel tag and identifying the flexible bag comprises information identifying the powder port.

10. The single-use bioreactor vessel of claim 1 , wherein the flexible bag further comprises at least one liquid port and wherein the readable information carried by the vessel tag and identifying the flexible bag comprises information identifying the at least one liquid port.

11. The single-use bioreactor vessel of claim 1 , further comprising:
a mixing device at a bottom side of the flexible bag, the mixing device being accessible from an exterior of the flexible bag and configured to be connected to an external motor for powering the mixing device; wherein:
the at least one sensor is mounted at a specified position spaced from the mixing device and positioned to be connected to an external connection when the mixing device is connected to the external motor, and
the vessel tag aligns with the tag reader when the port or the sensor is connected to an external connection and when the mixing device is connected to the external motor.

12. The single-use bioreactor vessel of claim 11 , wherein the readable information carried by the vessel tag and identifying the flexible bag comprises readable information identifying impeller characteristics.

13. The single-use bioreactor vessel of claim 1 , wherein the vessel tag further carries readable information pertaining to sensor calibration information of the at least one sensor.

14. The single-use bioreactor vessel of claim 1 , wherein the vessel tag further carries readable information pertaining to manufacturing date.

15. The single-use bioreactor vessel of claim 5 , wherein the readable information carried by the vessel tag and identifying the at least one sensor comprises:
information about sensor features of the at least one sensor, and
sensor calibration information of the at least one sensor.

16. The single-use bioreactor vessel of claim 1 , further comprising a tag reader disposed and configured for reading the readable information identifying the flexible bag and identifying the at least one sensor.

Assignees

• Sartorius Stedim Biotech Gmbh

Inventors

• Boettcher Lars
• Cutting Jonathan
• West Sharon D
• Oschwald Martin

Classifications

• C12M23/28

  disposable or single use · CPC title

• C12M27/02

  Stirrer or mobile mixing elements · CPC title

• B65D25/205

  Means for the attachment of labels, cards, coupons or the like; (cards or coupons for the other types of rigid or semi-rigid containers B65D25/36 takes precedence) · CPC title

• G06K7/10366

  the interrogation device being adapted for miscellaneous applications · CPC title

• C12M23/14

  Bags · CPC title