Compositions and methods to promote wound healing

US10478394B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10478394-B2
Application numberUS-201615557407-A
CountryUS
Kind codeB2
Filing dateMar 10, 2016
Priority dateMar 11, 2015
Publication dateNov 19, 2019
Grant dateNov 19, 2019

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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Abstract

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The present disclosure describes compositions and methods to promote wound healing. The compositions and methods include an interleukin-1 beta (IL-1B) receptor antagonist (IL-1Ra), such as anakinra.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of promoting healing of a chronic wound in a diabetic subject comprising administering to the chronic wound a therapeutically effective amount of a gel comprising a therapeutic agent consisting of a therapeutic protein consisting of the sequence provided in SEQ ID NO: 26 (anakinra), thereby promoting healing of the chronic wound. 2. The method of claim 1 , wherein the chronic wound is a diabetic ulcer. 3. The method of claim 1 , wherein the administering is topically administering. 4. The method of claim 1 , further comprising applying a wound dressing to the wound. 5. The method of claim 4 , wherein the administering and applying are achieved in one step. 6. The method of claim 4 , wherein the wound dressing is an adhesive bandage. 7. The method of claim 1 further comprising administering a platelet-derived growth factor and/or Becaplermin.

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Frequently asked questions

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What does patent US10478394B2 cover?
The present disclosure describes compositions and methods to promote wound healing. The compositions and methods include an interleukin-1 beta (IL-1B) receptor antagonist (IL-1Ra), such as anakinra.
Who is the assignee on this patent?
Univ Wayne State
What technology area does this patent fall under?
Primary CPC classification C07K14/545. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Nov 19 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).