Extracts of Isochrysis sp.

Patent metadata

Field	Value
Publication number	US-10463891-B2
Application number	US-56847509-A
Country	US
Kind code	B2
Filing date	Sep 28, 2009
Priority date	Sep 30, 2008
Publication date	Nov 5, 2019
Grant date	Nov 5, 2019

Abstract

The present invention relates to extracts of Isochrysis sp., preferably Tahitian Isochrysis , its cosmetic, dermatological and/or therapeutic uses and compositions and cosmetic, dermatological or therapeutic products comprising such an extract of Isochrysis sp., preferably Tahitian Isochrysis.

First claim

It is claimed:

1. A method for promoting pigmentation of hair and/or skin in a human subject in need thereof, comprising topically applying to the hair and/or skin of the subject a composition comprising an effective amount of an extract of Tahitian Isochrysis , wherein the extract of Tahitian Isochrysis is obtained by the method consisting essentially of the following steps:
(i) cultivating Tahitian Isochrysis sp. cells;
(ii) harvesting the cultivated Tahitian Isochrysis cells to obtain completely or substantially intact cell material;
(iii) optionally, washing and/or freeze-drying the completely or substantially intact cell material to provide a washed and/or freeze-dried cell material;
(iv) extracting the completely or substantially intact cell material or the washed and/or freeze-dried cell material with a solvent selected from the group consisting of hexane, ethyl acetate, ethanol, water, methanol, isopropanol, and a combination thereof for up to 24 h at a temperature of not more than 50° C. to provide an extract and extracted cell material; and
(v) separating the extract from the extracted cell material, and
wherein the composition is a cosmetic, dermatological, or therapeutic composition selected from the group consisting of a sunscreen composition, a self-tanning composition, a shaving composition, an after-shave, a deodorant, an antiperspirant, a shampoo, a conditioner, a hair tonic, a hair lotion, a hair rinse, a styling cream, a hair-setting composition, a styling aid, a blonding composition, a hair-coloring composition, or a decorative cosmetic.

2. The method of claim 1 , wherein the solvent in step (iv) is at least one of hexane, ethyl acetate, water, and methanol.

3. The method of claim 1 , wherein step (iv) occurs in the dark and/or under agitation.

4. A method for promoting pigmentation of hair and/or skin in a human subject in need thereof, comprising orally administering to the subject a composition comprising an effective amount of an extract of Tahitian Isochrysis , wherein the extract of Tahitian Isochrysis is at least one of a hexane, ethyl acetate, ethanol, water, methanol or isopropanol extract of Tahitian Isochrysis sp., wherein the extract is obtained by the method consisting essentially of the following steps:
(i) cultivating Tahitian Isochrysis sp. cells;
(ii) harvesting the cultivated Tahitian Isochrysis cells to obtain completely or substantially intact cell material;
(iii) optionally, washing and/or freeze-drying the completely or substantially intact cell material to provide a washed and/or freeze-dried cell material;
(iv) extracting the completely or substantially intact cell material or the washed and/or freeze-dried cell material with a solvent selected from the group consisting of hexane, ethyl acetate, ethanol, water, methanol, isopropanol, and a combination thereof for up to 24 h at a temperature of not more than 50° C. to provide an extract and extracted cell material; and
(v) separating the extract from the extracted cell material, and
wherein the composition in a form selected from the group consisting of a tablet, a dragee, a capsule, juice, a solution, granules and a foodstuff.

5. The method of claim 4 , wherein step (iv) occurs in the dark and/or under agitation.

6. The method of claim 4 , wherein the solvent in step (iv) is at least one of hexane, ethyl acetate, water, and methanol.

Assignees

• Herrmann Martina
• Joppe Holger
• Pertile Paolo
• Zanella Lorenzo
• Symrise Ag

Inventors

• Herrmann Martina
• Joppe Holger
• Pertile Paolo
• Zanella Lorenzo

Classifications

• A61P17/16

  Emollients or protectives, e.g. against radiation · CPC title

• A61P17/14

  for baldness or alopecia · CPC title

• A61P17/00

  Drugs for dermatological disorders · CPC title

• A61K8/9789

  Magnoliopsida [dicotyledons] · CPC title

• A61K8/9711 Primary

  Phaeophycota or Phaeophyta [brown algae], e.g. Fucus · CPC title