Cosmetic compositions

Patent metadata

Field	Value
Publication number	US-9333230-B2
Application number	US-201414202840-A
Country	US
Kind code	B2
Filing date	Mar 10, 2014
Priority date	Mar 14, 2013
Publication date	May 10, 2016
Grant date	May 10, 2016

Abstract

Disclosed is a composition and methods for its use capable of treating pruritus comprising a combination of one or more of an Echinacea purpurea extract, a Silybum marianum extract, glycerin, and a mixture comprising cetylhydroxyproline palmitamide/steric acid/ Brassica campestris (rapeseed) sterols.

First claim

The invention claimed is:

1. A method for treating pruritus comprising topically applying a composition that includes an effective amount of an aqueous extract from the whole plant of Echinacea purpurea , an aqueous extract from Silybum marianum fruit, glycerin, and a mixture comprising cetylhydroxyproline palmitamide and stearic acid and Brassica campestris (rapeseed) sterols to skin in need thereof, wherein topical application of the composition treats pruritus.

2. The method of method claim 1 , wherein the composition activates human cannabinoid receptor type 2 and inhibits fatty acid amide hydrolase activity in the skin.

3. The method of claim 1 , wherein the composition is formulated as a cream, lotion, emulsion, serum, or cleanser.

4. The method of claim 1 , wherein the composition is an oil-in-water emulsion or a water-in-oil emulsion.

5. The method of claim 1 , wherein said effective amount of the aqueous extract from the whole plant of Echinacea purpurea is 0.001 to 10% by weight of the composition,
wherein the effective amount of the aqueous extract from Silybum marianum fruit is 0.001 to 10% by weight of the composition and
wherein the effective amount of the mixture comprising cetylhydroxyproline palmitamide and stearic acid and Brassica campestris (rapeseed) sterols is 0.001 to 10% by weight of the composition.

6. The method of claim 5 , wherein said effective amount of the aqueous extract from the whole plant of Echinacea purpurea is 0.50% by weight of the composition,
wherein the effective amount of the aqueous extract from Silybum marianum fruit is 1.0% by weight of the composition and
wherein the effective amount of the mixture comprising cetylhydroxyproline palmitamide and stearic acid and Brassica campestris (rapeseed) sterols is 2.0% by weight of the composition.

7. The method of claim 6 , wherein said effective amount of glycerin is 15% by weight of the composition.

8. The method of claim 1 , wherein the composition is applied to the skin and remains on the skin for at least 5 minutes after topical application.

9. The method of claim 1 , wherein the skin in need of treatment is facial skin, leg skin, ankle skin, arm skin, hand skin, or scalp skin.

10. The method of claim 1 , wherein the composition further comprises at least one of a moisturization agent, a UV absorbing agent, anti-oxidant, structuring agent, emulsifier, silicone containing compound, essential oil, thickening agent, and a preservative.

11. The method of claim 1 , wherein the composition further comprises a pharmaceutical ingredient.

12. A method for reducing symptoms associated with pruritus comprising topically applying a composition that includes an effective amount of an aqueous extract from the whole plant of Echinacea purpurea , an aqueous extract from Silybum marianum fruit, glycerin, and a mixture comprising cetylhydroxyproline palmitamide and stearic acid and Brassica campestris (rapeseed) sterols to skin in need thereof, wherein topical application of the composition reduces symptoms associated with pruritus.

13. A method of treating pruritus comprising topically applying to pruritic skin a composition comprising:
(a) an aqueous extract from the whole plant of Echinacea purpurea extract and an aqueous extract from Silybum marianum fruit extract, wherein the combination of said extracts activates human cannabinoid receptor type 2 and inhibits fatty acid amide hydrolase activity in said pruritic skin; and
(b) glycerin and a mixture comprising cetylhydroxyproline palmitamide and stearic acid and Brassica campestris (rapeseed) sterols, wherein the combination of glycerin and the mixture comprising cetylhydroxyproline palmitamide and stearic acid and Brassica campestris (rapeseed) sterols moisturizes said pruritic skin.

Assignees

• Mary Kay Inc

Inventors

• Florence Tiffany

Classifications

• A61P17/04

  Antipruritics · CPC title

• A61P17/00

  Drugs for dermatological disorders · CPC title

• A61K31/401

  Proline; Derivatives thereof, e.g. captopril · CPC title

• A61K8/9767

  Pinaceae [Pine family], e.g. pine or cedar · CPC title

• A61K31/047

  having two or more hydroxy groups, e.g. sorbitol · CPC title