Polymer laminate

Patent metadata

Field	Value
Publication number	US-10456503-B2
Application number	US-201515305460-A
Country	US
Kind code	B2
Filing date	Apr 20, 2015
Priority date	Apr 24, 2014
Publication date	Oct 29, 2019
Grant date	Oct 29, 2019

Abstract

A polymer laminate has 2-100 layers each containing a biodegradable resin and having a thickness of 10 nm-400 nm that are laminated, the thickness of at least one of the outermost layers is 10 nm-180 nm, and the outermost layers are joined to each other. A polymer laminate excellent in biocompatibility and mechanical strength and suitable to medical applications such as wound dressings and antiadhesive materials can be obtained.

First claim

The invention claimed is:

1. A polymer laminate, comprising:
2-100 layers each containing a biodegradable resin and having a thickness of 10 nm-400 nm, a thickness of at least one of outermost layers is 10 nm-180 nm, and
a joint portion joining said outermost layers at pinpoints, at a part of an end portion of the laminate, at an entire part of the end portion of the laminate, or combinations thereof,
wherein layers other than the outermost layers may be joined or may not be joined to the outermost layers, and
said at least one of outermost layers contains a polylactic acid-based resin.

2. The polymer laminate according to claim 1 , wherein at least one layer of said layers having a thickness of 10 nm-400 nm contains a compound selected from the group consisting of a polysaccharide, a polyvinyl alcohol and a polyvinyl alcohol copolymer.

3. The polymer laminate according to claim 2 , wherein said polysaccharide is an alginate.

4. The polymer laminate according to claim 1 , wherein a total thickness of the polymer laminate is 20 nm-1,000 nm.

5. The polymer laminate according to claim 1 , wherein a hydrophobic chemical is contained in at least one layer of said layers having a thickness of 10 nm-400 nm.

6. The polymer laminate according to claim 1 , wherein a water soluble chemical is contained in at least one layer of said layers having a thickness of 10 nm-400 nm.

7. The polymer laminate according to claim 1 , wherein particles having a particle diameter of 5 nm to 5,000 nm are contained in at least one interlaminar part formed between said layers having a thickness of 10 nm-400 nm.

8. The polymer laminate according to claim 2 , wherein a total thickness of the polymer laminate is 20 nm-1,000 nm.

9. The polymer laminate according to claim 3 , wherein a total thickness of the polymer laminate is 20 nm-1,000 nm.

10. The polymer laminate according to claim 2 , wherein a hydrophobic chemical is contained in at least one layer of said layers having a thickness of 10 nm-400 nm.

11. The polymer laminate according to claim 3 , wherein a hydrophobic chemical is contained in at least one layer of said layers having a thickness of 10 nm-400 nm.

12. The polymer laminate according to claim 4 , wherein a hydrophobic chemical is contained in at least one layer of said layers having a thickness of 10 nm-400 nm.

13. The polymer laminate according to claim 2 , wherein a water soluble chemical is contained in at least one layer of said layers having a thickness of 10 nm-400 nm.

14. The polymer laminate according to claim 3 , wherein a water soluble chemical is contained in at least one layer of said layers having a thickness of 10 nm-400 nm.

15. The polymer laminate according to claim 4 , wherein a water soluble chemical is contained in at least one layer of said layers having a thickness of 10 nm-400 nm.

Assignees

• Tokai Univ Educational System
• Toray Industries
• Toray Univ Educational System

Inventors

• Okamura Yosuke
• Nagase Yu
• KOMACHI Takuya
• Hochi Motonori
• SEKIDO Yuki
• Arakane Toru

Classifications

• A61L31/048

  obtained by reactions only involving carbon-to-carbon unsaturated bonds (A61L31/041 takes precedence) · CPC title

• B32B9/045

  of synthetic resin · CPC title

• A61L15/26

  Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof {(A61L15/225 takes precedence)} · CPC title

• B32B2307/73

  Hydrophobic · CPC title

• B32B7/05

  the layers not being connected over the whole surface, e.g. discontinuous connection or patterned connection (using interposed adhesives or bonding materials applied in spaced arrangements B32B7/14) · CPC title