Alkenyl sulfate ester or salt thereof

Patent metadata

Field	Value
Publication number	US-10364216-B2
Application number	US-201414917178-A
Country	US
Kind code	B2
Filing date	Aug 1, 2014
Priority date	Sep 19, 2013
Publication date	Jul 30, 2019
Grant date	Jul 30, 2019

Abstract

Provided are a novel compound useful for adjusting sweetness or saltiness or inhibiting ENaC, and use thereof.
An octenyl sulfate ester of the following Formula (1) or a salt thereof, wherein the wavy line represents any one of cis- or trans-configuration.

First claim

The invention claimed is:

1. A composition comprising an octenyl sulfate ester of Formula (1),

wherein the wavy line is either a cis- or trans-configuration, or a salt thereof,

and an additional sweetener other than the octenyl sulfate ester of Formula (1) or salt thereof.

2. The composition of claim 1 , wherein the composition is a food, feed, drug or quasi-drug.

3. The composition according to claim 1 , wherein the octenyl sulfate ester of Formula (1) or salt thereof inhibits the first taste of sweetness of the other sweetener.

4. The composition according to claim 3 , wherein the octenyl sulfate ester of Formula (1) or salt thereof reinforces the sweetness aftertaste of the other sweetener.

5. The composition according to claim 3 or 4 , wherein the other sweetener is glycyrrhizin.

6. A method for reinforcing the sweetness of a sweetener, the method comprising
(a) administering or taking an octenyl sulfate ester of Formula (1),

wherein the wavy line is either a cis- or trans-configuration, or a salt thereof,

followed by
(b) administering or taking a sweetener other than the octenyl sulfate ester of Formula (1) or salt thereof,
to or by a target.

7. The method according to claim 6 , wherein the aftertaste of the sweetener administered or taken in step (b) is reinforced.

8. A method of imparting sweetness to, or adjusting the sweetness of, a food or a drug, the method comprising adding an octenyl sulfate ester of Formula (1),

wherein the wavy line is either a cis- or trans-configuration,
or a salt thereof to the food or drug.

9. A composition comprising an epithelial sodium channel inhibitor that comprises
an octenyl sulfate ester of Formula (1),

wherein the wavy line is either a cis- or trans-configuration,
or a salt thereof,
as an active ingredient,
wherein the composition is a dentifrice, a mouthwash or a gingiva massage cream, and
wherein the composition also contains a salty substance.

10. The composition of claim 9 , wherein the composition is a mouthwash.

11. A method of inhibiting the saltiness of a composition comprising a salty substance, the method comprising
(a) administering or taking a saltiness inhibiting amount of an octenyl sulfate ester of Formula (1):

wherein the wavy line is either cis- or trans-configuration, or a salt thereof and,

(b) administering or taking the composition that comprises the salty substance to or by a target in need of the inhibiting.

12. The method according to claim 11 , wherein the composition comprising the salty substance is a composition comprising mineral-derived metal ion and/or chloride ion, or metal chloride consisting of the metal ion and chloride ion.

13. The method according to claim 12 , wherein the mineral is at least one metal selected from the group consisting of sodium, potassium, calcium, magnesium and phosphorus.

14. The method according to claim 11 , wherein the composition is a food or an oral composition.

15. A method of inhibiting an epithelial sodium channel, the method comprising administering or taking of an effective amount of the octenyl sulfate ester of Formula (1):

wherein the wavy line is either a cis- or trans-configuration,

or a salt thereof
to or by a target in need thereof.

Assignees

• Kao Corp

Inventors

• Matsuura Masanori
• Nakagawa Tomohiro
• Yoshikawa Keiichi

Classifications

• A23V2002/00

  Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title

• A23L27/88

  Taste or flavour enhancing agents · CPC title

• C07C305/14 Primary

  being acyclic and unsaturated · CPC title

• A23L27/39

  Addition of sweetness inhibitors · CPC title