Bioreactor assembly
US-2019264157-A1 · Aug 29, 2019 · US
US10363528B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10363528-B2 |
| Application number | US-201515125594-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 16, 2015 |
| Priority date | Apr 16, 2014 |
| Publication date | Jul 30, 2019 |
| Grant date | Jul 30, 2019 |
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A mixing and thawing device (1) has a rocker drive (2) and a bag holder (3) for holding a bag (7). The bag holder (3) has a base part (8) and a lid part (9) that enclose a holding space (10) for the bag (7). A heating element (11) is arranged in the base part (8). Thus, the holding space (10) is designed as a heat-insulating closed chamber. Interconnected intermediate spaces (14, 15) are arranged between the bag (7) and the base part (8) and between the bag (7) and the lid part (9). One or more flow generators (16) are provided to generate a circulating fluid flow (17).
Opening claim text (preview).
The invention claimed is: 1. A mixing and thawing device ( 1 ), comprising: a rocker drive ( 2 ) having a substructure ( 4 ) and a rocker plate ( 5 ) that is configured for pivoting relative to the substructure ( 4 ) about a rocker axis ( 6 ) at a programmable frequency and a programmable angle; a bag holder ( 3 ) having a base part ( 8 ) and a lid part ( 9 ) that enclose a holding space ( 10 ) for holding a bag ( 7 ), the holding space ( 10 ) being a heat-insulating closed chamber, the base part ( 8 ) of the bag holder ( 3 ) being fastened securely to the rocker plate ( 5 ); a heating element ( 11 ) being arranged in the base part ( 8 ) a first intermediate space ( 14 ) arranged between the bag ( 7 ) and the base part ( 8 ); a second intermediate space ( 15 ) arranged between the bag ( 7 ) and the lid part ( 9 ) and in fluidic communication with the first intermediate space; and at least one flow generator ( 16 ) for generating a circulating fluid flow ( 17 ) through the first and second intermediate spaces ( 14 , 15 ) and on opposite sides of the bag ( 7 ). 2. The mixing and thawing device of claim 1 , wherein the at least one flow generator is a fan and the fluid flow is an air stream. 3. The mixing and thawing device of claim 1 , further comprising a lower part ( 12 ) arranged in the holding space ( 10 ) adjacent to the base part ( 8 ) and an upper part ( 13 ) arranged in the holding space ( 10 ) adjacent to the lid part ( 9 ). 4. The mixing and thawing device of claim 3 , wherein the lower part ( 12 ) and the upper part ( 13 ) form a protective housing for the bag ( 7 ). 5. The mixing and thawing device of claim 1 , wherein the base part ( 8 ) has one or more condensate outlets ( 18 ). 6. The mixing and thawing device of claim 3 , wherein the bag ( 7 ) is fastened between the lower part ( 12 ) and the upper part ( 13 ) to prevent slippage. 7. The mixing and thawing device of claim 1 , wherein the lid part ( 9 ) is removable from the base part ( 8 ). 8. The mixing and thawing device of claim 1 , further comprising a heat-conducting gel pad ( 19 ) arranged on the heating element ( 11 ) and facing the bag ( 7 ). 9. The mixing and thawing device of claim 8 , wherein the gel pad ( 19 ) is flexible. 10. The mixing and thawing device of claim 8 , wherein the heat-conducting gel pad regulates a temperature of the heating element. 11. The mixing and thawing device of claim 1 , further comprising one or more temperature sensor arranged within the bag holder ( 3 ). 12. The mixing and thawing device of claim 1 , further comprising a control and regulation device arranged within the rocker drive ( 2 ) for controlling and regulating a thawing and/or mixing that can be performed using the mixing and thawing device ( 1 ). 13. The mixing and thawing device of claim 12 , wherein the control and regulation device is operable to operate the rocker drive ( 2 ) selectively for carrying out the mixing without heating or temperature-controlling the bag ( 7 ). 14. The mixing and thawing device of claim 3 , wherein the lower part ( 12 ) and/or the upper part ( 13 ) are bowl-shaped.
by gas flow · CPC title
Operations & Transport · mapped topic
having means for cooling or heating the devices or media · CPC title
the media being heated in the reservoir, e.g. warming bloodbags · CPC title
Operations & Transport · mapped topic
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