Powderous vitamin E formulations

Patent metadata

Field	Value
Publication number	US-10362800-B2
Application number	US-201113976696-A
Country	US
Kind code	B2
Filing date	Dec 27, 2011
Priority date	Dec 27, 2010
Publication date	Jul 30, 2019
Grant date	Jul 30, 2019

Abstract

The present invention relates to improved vitamin E formulations, as well as to the production of such formulations.

First claim

The invention claimed is:

1. A powderous formulation comprising:
(i) at least 40 wt-%, based on the total weight of the powderous formulation, of a porous particulate carrier material,
(ii) at least 50 wt-%, based on the total weight of the powderous formulation, of vitamin E coated onto the porous particulate carrier material, and
(iii) 0.5 wt-%-8 wt-%, based on the total weight of the powderous formulation, of at least one auxiliary compound selected from the group consisting of aluminium ammonium sulphate, aluminium potassium sulfate, ammonium acetate, ammonium bisulphite, ammonium carbonate, ammonium chloride, ammonium dihydrogen phosphate ammonium hydrogen carbonate, bentonite, montmorillonite, calcium aluminates, calcium carbonate, calcium silicate, synthetic calcium sulphate di-hydrate, calcium sulfate, kaolinitic clays, diatomaceous earth, perlite, potassium bisulphite, potassium hydrogen carbonate, potassium sulphate, potassium carbonate, sepiolitic clays, silicic acid, synthetic sodium aluminosilicate, sodium aluminosulfate, sodium bisulphate, sodium carbonate, sodium chloride, sodium hydrogen carbonate, sodium sulphate, vermiculite, calcium carbonate, magnesium carbonate, calcareous marine algae, magnesium oxide, magnesium sulphate, dicalcium phosphate, tri-calcium phosphate, dicalcium phosphate, defluorinated rock-phosphate, monocalcium phosphate, calcium-magnesium phosphate, mono-ammonium phosphate, magnesium phosphate, sodium-calcium-magnesium phosphate, mono-sodium phosphate, glycerol, propylene glycol, glyceryl triacetate, sorbitol, polydextrose, lactic acid and urea, wherein
the at least one auxiliary compound has an average particle size (d 0.5) of 54-100 μm in the formulation, and wherein
the powderous formulation has a minimum ignition energy (MIE) value according to EN 13821:2002 of 10 to 1000 mJ.

2. The powderous formulation according to claim 1 , which further comprises:
(iv) 0 to 5 wt-%, based on the total weight of the powderous formulation, of water.

3. The powderous formulation according to claim 1 , wherein the carrier material is selected from the group consisting of synthetically produced precipitated silica, proteins, starches, lignosulfonates and gums.

4. The powderous formulation according to claim 1 wherein the at least one auxiliary compound is selected from the group consisting of ammonium dihydrogen phosphate, purified diatomaceous earth, potassium hydrogen carbonate, potassium sulphate, potassium carbonate, sodium chloride, sodium sulphate and sodium hydrogen carbonate.

5. Food, feed or personal care products comprising a formulation of claim 1 .

6. A powderous formulation comprising:
(i) at least 40 wt-%, based on the total weigh of the powderous formulation, of a porous particulate carrier material,
(ii) at least 50 wt-%, based on the total weight of the powderous formulation, of vitamin E coated onto the porous particulate carrier material, and
(iii) 0.5 wt-%-8 wt-%, based on the total weight of the powderous formulation, of sodium chloride as an auxiliary compound having an average particle size (d 0.5) in the formulation of 54 μm to 100 μm, wherein
the powderous formulation has a minimum ignition energy (MIE) value according to EN 13821:2002 of 30-100 mJ.

7. The powderous formulation according to claim 6 , which further comprises:
(iv) 0 to 5 wt-%, based on the total weight of the powderous formulation, of water.

8. The powderous formulation according to claim 6 , wherein the carrier material is chosen from the group consisting of synthetically produced precipitated silica, proteins, starches, lignosulfonates and gums.

9. The powderous formulation according to claim 6 , wherein the vitamin E is coated onto a mixture of the particulate porous carrier and sodium chloride.

Assignees

• Gadient Martin
• Lindemann Thomas
• Schwaninger Mischa
• Voelker Karl Manfred
• Urban Kai
• Kirchen Stefanie
• Dsm Ip Assets Bv

Inventors

• Gadient Martin
• Lindemann Thomas
• Schwaninger Mischa
• Voelker Karl Manfred
• Urban Kai
• Kirchen Stefanie

Classifications

• A61P3/02

  Nutrients, e.g. vitamins, minerals · CPC title

• A61Q19/00

  Preparations for care of the skin · CPC title

• A61K9/1676

  having a drug-free core with discrete complete coating layer containing drug (adsorbates of liquid drug formulations on inert powders without simultaneous granulation step A61K9/141; with further drug-free outer coating A61K9/5078; drug conjugated to non-active particles A61K47/6921) · CPC title

• A61K8/0241

  Containing particulates characterized by their shape and/or structure (see also A61K8/04, A61K8/11, and A61K8/14, further aspects are classified in A61K2800/40 and subcodes) · CPC title

• A23L33/15

  Vitamins · CPC title