Probiotic bacterial strains and symbiotic composition containing the same intended for infant food

Patent metadata

Field	Value
Publication number	US-10286017-B2
Application number	US-201214116999-A
Country	US
Kind code	B2
Filing date	May 9, 2012
Priority date	May 9, 2011
Publication date	May 14, 2019
Grant date	May 14, 2019

Abstract

Selection of probiotic strains belonging to the genus Bifidobacterium and to a symbiotic composition containing the same for use of feeding infants, is described.

First claim

The invention claimed is:

1. A method for treatment of colic, diarrhea and intestinal disorders in a subject of pediatric age, the method comprising:
administering to the subject an effective amount of a food composition or supplement product or pharmaceutical composition,
the food composition or supplement product or pharmaceutical composition comprising a bacterial mixture, said bacterial mixture comprising at least one viable bacterial strain belonging to the species Bifidobacterium breve , and a bacterial strain belonging to the species Bifidobacterium longum or Bifidobacterium longum subsp. longum the bacterial mixture having an antimicrobial activity against the pathogens E. coli, Salmonella enteriditis, Clostridium difficile and Campylobacter jejunii,

wherein the at least one viable bacterial strain belonging to the species Bifidobacterium breve comprises Bifidobacterium breve B632, deposited by the company Probiotical SpA of Novara (Italy) with the Depositary Institution DSMZ on Apr. 7, 2011 and having the deposit number DSM 24706.

2. The method according to claim 1 , wherein the at least one bacterial strain further comprises a bacterial strain belonging to the species Bifidobacterium breve selected from the group consisting of
Bifidobacterium breve B2274, deposited by the company Probiotical SpA of Novara (Italy) with the Depositary Institution DSMZ on Apr. 7, 2011 and having the deposit number DSM 24707;
Bifidobacterium breve B7840, deposited by the company Probiotical SpA of Novara, (Italy) with the Depositary Institution DSMZ on Apr. 7, 2011 and having the deposit number DSM 24708; and
Bifidobacterium breve BR03, deposited by the company Probiotical SpA of Novara (Italy) with the Depositary Institution DSMZ and having the deposit number DSM 16604.

3. The method according to claim 1 , wherein the strain belonging to the species Bifidobacterium longum is Bifidobacterium longum subsp. longum B1975, deposited by the company Probiotical SpA of Novara (Italy) with the Depositary Institution DSMZ on Apr. 7, 2011 and having the deposit number DSM 24709.

4. The method according to claim 1 , wherein the at least one bacterial strain further comprises Bifidobacterium breve BR03, deposited by the company Probiotical SpA of Novara (Italy) with the Depositary Institution DSMZ and having the deposit number DSM 16604.

5. The method according to claim 1 , wherein the bacterial mixture further comprises Bifidobacterium breve BR03, deposited by the company Probiotical SpA of Novara (Italy) with the Depositary Institution DSMZ and having the deposit number DSM 16604, in association with Lactobacillus plantarum LPOI deposited by the company Mofin Srl of Novara (Italy) with the Depositary Institution BCCM-LMG on Oct. 16, 2001 and having the deposit number LMG P-21021.

6. The method according to claim 1 , wherein the food composition or supplement product or pharmaceutical composition comprising a bacterial mixture is added or suspended in a vegetable oil selected from among olive oil, corn oil, sunflower oil, seed oil and palm oil.

7. The method according to claim 6 , wherein the food composition or supplement product or pharmaceutical composition is a composition comprising at least one vegetable substance selected from the group comprising of sterols or phytosterols, stanols or phytostanols, glucomannan, konjac gum and/or at least one prebiotic fibre selected from the group comprising fructo-oligosaccharides FOS, galacto-oligosaccharides -GOS, xylo-oligosaccharides -XOS, inulin, larch fibre or arabinogalactan and/or fermented red rice and/or betaglucans from oats, oat bran, barley, barley bran and/or aloe arborescens gel in lyophilized form.

8. The method for the treatment of colic, diarrhea and intestinal disorders in subjects of pediatric age according to claim 6 , wherein the said food composition or supplement product or pharmaceutical composition is a composition comprising simethicone.

9. The method according to claim 1 , wherein the at least one bacterial strain further comprises
Bifidobacterium breve B2274, deposited by the company Probiotical SpA of Novara (Italy) with the Depositary Institution DSMZ on Apr. 7, 2011 and having the deposit number DSM 24707,
Bifidobacterium breve B7840, deposited by the company Probiotical SpA of Novara, (Italy) with the Depositary Institution DSMZ on Apr. 7, 2011 and having the deposit number DSM 24708; and
Bifidobacterium longum subsp. longum B1975, deposited by the company Probiotical SpA of Novara (Italy) with the Depositary Institution DSMZ on Apr. 7, 2011 and having the deposit number DSM 24709.

Assignees

• Mogna Giovanni
• Strozzi Gian Paolo
• Mogna Luca
• Probiotical Spa

Inventors

• Mogna Giovanni
• Strozzi Gian Paolo
• Mogna Luca

Classifications

• A61P31/04

  Antibacterial agents · CPC title

• A61P1/00

  Drugs for disorders of the alimentary tract or the digestive system · CPC title

• A61P1/12

  Antidiarrhoeals · CPC title

• A23L33/135

  Bacteria or derivatives thereof, e.g. probiotics · CPC title

• A61K35/74

  Bacteria (therapeutic use of a bacterial protein A61K38/00) · CPC title