Microarray package device and method of manufacturing the same
US-9187846-B2 · Nov 17, 2015 · US
US10246232B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10246232-B2 |
| Application number | US-201715466526-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 22, 2017 |
| Priority date | Aug 31, 2007 |
| Publication date | Apr 2, 2019 |
| Grant date | Apr 2, 2019 |
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A system includes a cap having an opening, and a septum configured to engage with the cap. The septum includes a first portion having a first width, and a second portion having a second width smaller than the first width. The second portion is sized and shaped to be received by the opening of the cap.
Opening claim text (preview).
What is claimed is: 1. A system comprising: a cap comprising an opening; and a septum configured to engage with the cap, the septum comprising: an annular shaped first portion having a first width, wherein the first portion comprises a rounded-wall portion; a second portion having a second width smaller than the first width, the second portion being sized and shaped to be received by the opening of the cap; a third portion adjacent the second portion, the third portion having a third width larger than the first width and the second width, wherein the third portion has a constant circumferential width from a top surface to a bottom surface of the third portion, wherein the bottom surface has a constant horizontal plane across the circumferential width of the third portion; and an inert coating disposed on the bottom surface of the third portion defining a terminal end of the septum. 2. The system of claim 1 , wherein at least one of the first width or the third width is larger than a width of the opening of the cap. 3. The system of claim 1 , wherein the second portion is between the first portion and the third portion. 4. The system of claim 1 , wherein the second portion has a thickness substantially equal to or greater than a thickness of the cap. 5. The system of claim 1 , wherein at least the first portion, the second portion, or the third portion comprises an elastomeric material. 6. The system of claim 5 , wherein the elastomeric material comprises silicone. 7. The system of claim 1 , wherein the inert coating comprises polytetrafluoroethylene, polypropylene, biaxially-oriented polypropylene, high density polyethylene, or fluorinated ethylene-propylene. 8. The system of claim 1 , wherein the first width is larger than a width of the opening of the cap, and the first portion is resiliently deformable having the rounded wall portion to be passable through the opening of the cap. 9. The system of claim 1 , wherein at least the first portion, the second portion, or the third portion have a thickness that is at least partially hollow. 10. The system of claim 1 , further comprising a vessel configured to engage with the cap. 11. The system of claim 10 , wherein the septum is configured for puncture for fluid movement through the septum and to the vessel, from the vessel, or combination thereof. 12. The system of claim 10 , wherein the vessel has an inner surface and the septum is sized and shaped to contact and to seal the inner surface when the vessel and the cap are engaged. 13. The system of claim 12 , wherein the inner surface of the vessel has a contour that substantially matches the outer contour of the third portion to form the seal when the vessel and the cap are engaged. 14. The system of claim 12 , wherein the vessel has a lip having an upper surface, and the third portion of the septum includes a portion that compresses against the lip when the vessel and the cap are engaged. 15. The system of claim 14 , wherein the third portion of the septum includes a horizontal lower surface sized and shaped to compress against the upper surface of the lip of the vessel and form the seal. 16. The system of claim 1 , wherein the second and third portions are annular in shape. 17. A method of inserting the elastomeric septum of claim 1 into a cap opening, the method comprising: deflecting the walls of the annular shaped portion of the septum inwardly to allow the portion to pass through the cap opening; pressing the annular shaped portion of the septum through the cap opening; and allowing the annular shaped portion to expand back to its original shape after passing through the cap opening. 18. The method of claim 17 , wherein the third portion of the septum provides a stop to prevent pressing the septum completely through the cap opening. 19. A system comprising: a cap comprising an opening; a septum configured to engage with the cap, the septum comprising: an annular shaped first portion having a first width, wherein the first portion comprises a rounded-wall portion; a second portion having a second width smaller than the first width, the second portion being sized and shaped to be received by the opening of the cap; a third portion adjacent the second portion, the third portion having a third width larger than the first width and the second width, wherein the third portion has a constant circumferential width from a top surface to a top surface to a bottom surface of the third portion, wherein the bottom surface has a constant horizontal plane across the circumferential width of the third portion; and an inert coating disposed on the bottom surface of the third portion defining a terminal end of the septum; and a vessel configured to engage with the cap, wherein the septum is configured for puncture for fluid movement through the septum and to the vessel, from the vessel, or combination thereof. 20. The system of claim 19 , wherein the vessel has an inner surface and the septum is sized and shaped to contact and to seal the inner surface when the vessel and the cap are engaged.
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