Measuring biological tissue parameters using diffusion magnetic resonance imaging
US-9404986-B2 · Aug 2, 2016 · US
US10241182B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10241182-B2 |
| Application number | US-201314651496-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 6, 2013 |
| Priority date | Dec 12, 2012 |
| Publication date | Mar 26, 2019 |
| Grant date | Mar 26, 2019 |
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A magnetic resonance imaging system (1) includes at least one processor (28) configured to receive (48) diffusion weighted imaging data based on a diffusion weighted imaging sequence with magnetic gradient fields applied in different directions and with different b-values. The at least one processor (28) is further configured to detect (50) motion corrupted data present in the received imaging data based on a comparison of data redundant in the received data, and substitute (52) alternative data for detected motion corrupted data.
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What is claimed is: 1. A magnetic resonance imaging system, comprising: at least one processor programmed to: receive diffusion weighted imaging data from a region of interest of a subject based on a diffusion weighted imaging sequence with magnetic gradient fields applied in different directions and with different b-values; detect motion corrupted data present in the received imaging data based on a comparison of data redundant in the received data, the data redundancy existing from the diffusion weighted imaging data received for the magnetic gradient fields applied in three orthogonal directions, the motion corrupted data being detected by comparing the diffusion weighted imaging data from two of the three orthogonal directions with the diffusion weighted imaging data from a third orthogonal gradient field measure of a third of the three orthogonal directions; and substitute alternative data for detected motion corrupted data. 2. The system according to claim 1 , wherein the at least one processor is further programmed to determine a direction of repetitive motion based on the comparison of data redundant in the received diffusion weighted imaging data, and wherein the system further comprises: a repetitive motion monitoring unit which determines a time interval of expected repetitive motion of a subject; and a gradient motion control unit which adjusts for acquisition of the diffusion weighted imaging data directional sensitivity of applied gradient fields to be sensitive orthogonal to the direction of the repetitive motion during the determined time interval. 3. The system according to claim 2 , wherein the gradient motion control unit adjusts the directional sensitivity of the applied gradients fields to be sensitive in the direction of repetitive motion during an interval when no repetitive motion is expected. 4. The system according to claim 2 , wherein the repetitive motion monitoring unit includes at least one of: a respiratory monitor operatively connected to the subject and configured to determine time intervals of respiratory motion; and an electrocardiogram monitor operatively connected to the subject and configured to determine time intervals of cardiac motion. 5. The system according to claim 1 , wherein the compared redundant data includes data from exponential signal decay rates. 6. The system according to claim 5 , wherein the compared redundant data includes data with similar b-values applied in different spatial directions. 7. The system according to claim 1 , wherein the diffusion weighted imaging sequence is modified to resample locations of the motion corrupted data. 8. A method of magnetic resonance imaging, comprising: receiving diffusion weighted imaging data from a region of interest of a subject based on a diffusion weighted imaging sequence with magnetic gradient fields applied in three orthogonal directions and with different b-values; detecting motion corrupted data present in the received imaging data based on a comparison of data redundant in the received data, the data redundancy existing from the diffusion weighted imaging data received for the magnetic gradient fields applied in the three orthogonal directions, the motion corrupted data being detected by comparing the diffusion weighted imaging data from two of the three orthogonal directions with the diffusion weighted imaging data from a third orthogonal gradient field measure of a third of the three orthogonal directions; and substituting alternative redundant data from the received data for detected motion corrupted data. 9. The method according to claim 8 , further comprising: determining an expected time interval of repetitive motion of a subject; and adjusting acquisition of the diffusion weighted imaging data directional sensitivity of applied gradient fields to be sensitive orthogonal to a direction of the repetitive motion during the determined time interval, the direction being determined based on the comparison of data redundant in the received diffusion weighted imaging data. 10. The method according to claim 8 , further comprising: determining an expected time interval of repetitive motion of a subject; and adjusting the directional sensitivity of the applied gradients fields to be sensitive in the direction of repetitive motion during an interval when no repetitive motion is expected. 11. The method according to claim 8 , wherein the compared redundant data includes data from at least one of: different directional gradients; exponential signal decay rates; or similar b-values applied in different spatial directions. 12. The method according to claim 8 , wherein the substituted alternative redundant data includes received data with different directional gradient fields and/or different b-values compared with the detected motion corrupted data. 13. A non-transitory computer-readable storage medium carrying software which controls one or more electronic data processing devices to perform the method according to claim 12 . 14. An electronic data processing device configured to perform the method according to claim 12 . 15. A magnetic resonance system, comprising: a processor programmed to: receive diffusion weighted imaging data based on a diffusion weighted imaging sequence with magnetic gradient fields applied in different directions and with different b-values; detect motion corrupted data present in the received imaging data based on a comparison of data redundant in the received data, the data redundancy existing from the diffusion weighted imaging data received for the magnetic gradient fields applied in the three orthogonal directions, the motion corrupted data being detected by comparing the diffusion weighted imaging data from two of the three orthogonal directions with the diffusion weighted imaging data from a third orthogonal gradient field measure of a third of the three orthogonal directions; and substitute alternative data for detected motion corrupted data; a repetitive motion monitoring unit which determines an expected time interval of repetitive motion of a subject; and a gradient motion control unit which adjusts for acquisition of the diffusion weighted imaging data of the subject with a directional sensitivity of the applied magnetic gradient fields along three axes to be sensitive orthogonal to a direction of repetitive motion during the determined time interval. 16. The system according to claim 15 , wherein the repetitive motion monitoring unit includes at least one of: a respiratory monitor operatively connected to the subject which determines time intervals of respiratory motion; or an electrocardiogram monitor operatively connected to the subject which determines time intervals of cardiac motion. 17. The system according to claim 15 , wherein the processor is further programmed to: determine a direction of repetitive motion based on the comparison of data redundant in the received diffusion weighted imaging data. 18. The system according to claim 15 , wherein the processor is further programmed to: determine an expected time interval of repetitive motion of a subject; and adjust acquisition of the diffusion weighted imaging data directional sensitivity of applied gradient fields to be sensitive orthogonal to a direction of the repetitive motion during the determined time interval, the direction being determined based on the comparison of data redundant in the received diffusion weighted imaging data. 19. The system according to claim 15 , wherein the processor is further programmed to: determine an expected time interval of repetitive motion
Diffusion imaging · CPC title
using B1 gradients, e.g. rotating frame techniques, use of surface coils · CPC title
due to motion, displacement or flow, e.g. gradient moment nulling (G01R33/567 takes precedence) · CPC title
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