Shaped bone graft materials and methods of use

Patent metadata

Field	Value
Publication number	US-10194964-B2
Application number	US-201514941073-A
Country	US
Kind code	B2
Filing date	Nov 13, 2015
Priority date	Nov 14, 2014
Publication date	Feb 5, 2019
Grant date	Feb 5, 2019

Abstract

A bone material comprising a coherent mass of cartridge milled and demineralized bone fibers is provided, the coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a bone material comprising a lyophilized coherent mass of cartridge milled and demineralized bone fibers is provided, the lyophilized coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a method of making an implantable bone material is provided, the method comprising drying a coherent mass of cartridge milled and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass.

First claim

What is claimed is:

1. A bone material comprising a coherent mass of cartridge milled and demineralized bone fibers, the coherent mass of cartridge milled and demineralized bone fibers having no binder disposed in or on the coherent mass, wherein the bone material is contacted with a liquid to form a putty or a paste that hardens after implantation, wherein the bone material is a cylinder shaped bone material and the coherent mass has a plurality of channels running longitudinally through a center of the cylinder shaped bone material to allow fluid to hydrate the bone material.

2. A bone material of claim 1 , wherein the bone material comprises cortical bone, cancellous bone, cortico-cancellous bone, or mixtures thereof.

3. A bone material of claim 1 , wherein the bone material is obtained from autogenous bone, allogeneic bone, xenogeneic bone, or mixtures thereof.

4. A bone material of claim 1 , wherein the coherent mass is lyophilized.

5. A bone material of claim 1 , wherein the coherent mass has a plurality of channels running longitudinally through an exterior of the cylinder shaped bone material to allow fluid to hydrate the bone material.

Assignees

• Warsaw Orthopedic Inc

Inventors

• Schlachter Kelly W
• Shimko Daniel A
• Kalpakci Kerem N
• Vasquez Erick
• Kaes David R
• Bhattacharyya Subhabrata

Classifications

• A61L27/54

  Biologically active materials, e.g. therapeutic substances {(A61L27/227 takes precedence)} · CPC title

• A61B17/8805

  for introducing fluid filler into bone or extracting it (A61B17/7097, A61B17/8833 take precedence) · CPC title

• A61L27/3691

  characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation · CPC title

• A61B2017/8838

  for mixing bone cement or fluid fillers · CPC title

• A61F2002/2835

  Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material · CPC title