System and methods for sample processing with mass spectrometry incorporating magnetic beads
US-2024255473-A1 · Aug 1, 2024 · US
Low pollutant dialysis solution
US10088457B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10088457-B2 |
| Application number | US-201414901542-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 23, 2014 |
| Priority date | Jun 25, 2013 |
| Publication date | Oct 2, 2018 |
| Grant date | Oct 2, 2018 |
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Abstract
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A method for the determination of pollutants and leachables in a dialysis solution by stir bar sorptive extraction involves conditioning a sorptive material-coated stir bar, stirring the dialysis solution with the conditioned stir bar, desorbing of pollutants and leachables from the coated stir bar, and analyzing the desorbed pollutants and leachables by gas chromatography-mass spectrometry (GC-MS).
First claim
Opening claim text (preview).
The invention claimed is: 1. Method for determination of pollutants and leachables in a dialysis solution by stir bar sorptive extraction comprising the steps of conditioning a stir bar coated with a sorptive material by washing the coated stir bar in a mixture comprising methanol and dichloromethane, adding sodium chloride at a concentration of at least 90% saturation to the dialysis solution, stirring the dialysis solution with the conditioned coated stir bar, followed by desorption of pollutants and leachables from the coated stir bar, and analysis of the desorbed pollutants and leachables by gas chromatography-mass spectrometry (GC-MS). 2. Method of claim 1 , wherein the conditioning step additionally comprises ultrasonic treatment. 3. Method of claim 1 , wherein the sorptive material coating the stir bar is polydimethylsiloxane (PDMS).
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Heat (radiation A61L2/08) · CPC title
- G01N30/06Primary
Preparation · CPC title
including use of a solid sorbent, semipermeable membrane, or liquid extraction · CPC title
Inorganic carriers, supports or substrates · CPC title
interfaced to gas chromatograph (interfaces in general for introducing or extracting samples to be analysed with specially adapted mass spectrometer, see H01J49/04) · CPC title
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- What does patent US10088457B2 cover?
- A method for the determination of pollutants and leachables in a dialysis solution by stir bar sorptive extraction involves conditioning a sorptive material-coated stir bar, stirring the dialysis solution with the conditioned stir bar, desorbing of pollutants and leachables from the coated stir bar, and analyzing the desorbed pollutants and leachables by gas chromatography-mass spectrometry (GC…
- Who is the assignee on this patent?
- Fresenius Medical Care Deutschland Gmbh
- What technology area does this patent fall under?
- Primary CPC classification G01N30/06. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).