Biomedical patches with spatially arranged fibers

Patent metadata

Field	Value
Publication number	US-10080687-B2
Application number	US-201514664073-A
Country	US
Kind code	B2
Filing date	Mar 20, 2015
Priority date	Sep 21, 2012
Publication date	Sep 25, 2018
Grant date	Sep 25, 2018

Abstract

A structure for use in repairing a defect in a substrate is provided. The structure includes a first layer and a second layer coupled to the first layer using a first coupling process. The first layer is formed by a plurality of polymeric fibers, and the second layer has a plurality of densities formed by a plurality of polymeric fibers. The first and second layers of the structure are configured to separate after at least one of a predetermined time and an environmental condition.

First claim

What is claimed is:

1. A structure for use in repairing a defect in a substrate, the structure comprising:
a first layer formed by a first plurality of polymeric fibers; and
a second layer formed by a second plurality of polymeric fibers, the second layer coupled to the first layer using a first coupling process, the second layer having a plurality of densities formed by the second plurality of polymeric fibers, wherein the first and second layers are configured to separate after at least one of a predetermined time and an environmental condition and wherein the structure is configured to be applied to the substrate containing the defect.

2. A structure in accordance with claim 1 , further comprising a backing that is coupled to at least one of the first layer and the second layer, wherein the backing is coupled using a third coupling process.

3. A structure in accordance with claim 2 , wherein the backing is at least one of permeable and non-permeable.

4. A structure in accordance with claim 1 , wherein the first coupling process includes at least one of heating, applying mechanical stress, applying mechanical pressure, applying a glue, chemical processing, cross-linking, and surface functionalization.

5. A structure in accordance with claim 1 , wherein the first and second layer are configured to be applied to biological tissue.

6. A structure in accordance with claim 1 , further comprising a third layer that is coupled to the first and second layers using a second coupling process different than the first coupling process.

7. A structure in accordance with claim 1 , further comprising a third layer that is coupled to the first and second layers using the first coupling process.

Assignees

• Univ Washington

Inventors

• Macewan Matthew R

Classifications

• A61F13/00034 Primary

  Human Necessities · mapped topic

• A61F13/00017

  Human Necessities · mapped topic

• D04H1/4374

  using different kinds of webs, e.g. by layering webs · CPC title

• A61F13/00987

  Apparatus or processes for manufacturing non-adhesive dressings or bandages · CPC title

• D04H1/728

  by electro-spinning {(electro-spinning methods and apparatus D01D5/0007)} · CPC title