Acyclic nucleoside phosphonate diesters

US10076533B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10076533-B2
Application numberUS-201715809400-A
CountryUS
Kind codeB2
Filing dateNov 10, 2017
Priority dateMar 15, 2013
Publication dateSep 18, 2018
Grant dateSep 18, 2018

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present disclosure relates, inter alia, to compositions and methods for treating viral diseases and cancer. There are disclosed lipophilic antiviral and anticancer acyclic nucleoside phosphonate diesters, preparation thereof, and methods of using the compounds to treat viral diseases and cancer.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of treating cervical intraepithelial neoplasia, anal intraepithelial neoplasia, or vulvar intraepithelial neoplasia in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a compound of formula: or a pharmaceutically acceptable salt thereof, optionally in a pharmaceutically acceptable carrier. 2. The method of claim 1 , wherein the subject is a human. 3. The method of claim 1 , wherein the compound is topically administered as a topical formulation. 4. The method of claim 3 , wherein the topical formulation is a cream. 5. The method of claim 3 , wherein the topical formulation is a gel. 6. The method of claim 1 for treating cervical intraepithelial neoplasia. 7. The method of claim 6 , wherein the subject is a human. 8. The method of claim 6 , wherein the compound is topically administered as a topical formulation. 9. The method of claim 8 , wherein the topical formulation is a cream. 10. The method of claim 8 , wherein the topical formulation is a gel. 11. The method of claim 1 for treating anal intraepithelial neoplasia. 12. The method of claim 11 , wherein the subject is a human. 13. The method of claim 11 , wherein the compound is topically administered as a topical formulation. 14. The method of claim 13 , wherein the topical formulation is a cream. 15. The method of claim 13 , wherein the topical formulation is a gel. 16. The method of claim 1 for treating vulvar intraepithelial neoplasia. 17. The method of claim 16 , wherein the subject is a human. 18. The method of claim 16 , wherein the compound is topically administered as a topical formulation. 19. The method of claim 18 , wherein the topical formulation is a cream. 20. The method of claim 18 , wherein the topical formulation is a gel. 21. The method of claim 1 , wherein the cervical intraepithelial neoplasia, the anal intraepithelial neoplasia, or the vulvar intraepithelial neoplasia is caused by a human papilloma virus.

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What does patent US10076533B2 cover?
The present disclosure relates, inter alia, to compositions and methods for treating viral diseases and cancer. There are disclosed lipophilic antiviral and anticancer acyclic nucleoside phosphonate diesters, preparation thereof, and methods of using the compounds to treat viral diseases and cancer.
Who is the assignee on this patent?
Univ California
What technology area does this patent fall under?
Primary CPC classification C07F9/65616. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Sep 18 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 12 related publications on this page (citations in our corpus or others sharing the same primary CPC).