Robotic Microtool Control in an Intelligent Automated In Vitro Fertilization and Intracytoplasmic Sperm Injection Platform
US-2024426856-A1 · Dec 26, 2024 · US
Inorganic pyrophosphate and uses thereof
US10070889B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10070889-B2 |
| Application number | US-201414290818-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 29, 2014 |
| Priority date | Dec 9, 2011 |
| Publication date | Sep 11, 2018 |
| Grant date | Sep 11, 2018 |
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Abstract
Official abstract text for this publication.
The present invention provides a new and improved sperm stimulating additive comprising a certain amount of inorganic pyrophosphate (PPi). Addition of PPi in the media for human/animal in vitro fertilization (IVF) improves fertilization rate; addition of PPi in the semen extender for farm animal artificial insemination (AI) may improve pregnancy rates; furthermore, mammalian oocytes matured in vitro in a medium including PPi attain improved fertilization and developmental potential, while embryos cultured in medium supplemented with PPi have improved development to blastocyst.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of artificial insemination comprising providing sperm and inorganic pyrophosphate (PPi) to a reproductive tract of a female, wherein the concentration of PPi is between 1 μM to 200 μM. 2. The method of claim 1 , wherein the PPi is gradually released into the reproductive tract of the female. 3. The method of claim 1 , wherein the concentration of PPi is between 1 μM to 20 μM.
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Classifications
Whole embryos; Culture medium therefor · CPC title
Conditioning of cells for in vitro fecondation or nuclear transfer · CPC title
Sperm cells, spermatogonia · CPC title
involving human or animal cells (immunoassay G01N33/56966; immunoassays of protozoa G01N33/56905; protozoa in screening assays C12Q1/025) · CPC title
Human Necessities · mapped topic
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- What does patent US10070889B2 cover?
- The present invention provides a new and improved sperm stimulating additive comprising a certain amount of inorganic pyrophosphate (PPi). Addition of PPi in the media for human/animal in vitro fertilization (IVF) improves fertilization rate; addition of PPi in the semen extender for farm animal artificial insemination (AI) may improve pregnancy rates; furthermore, mammalian oocytes matured in …
- Who is the assignee on this patent?
- Sutovsky Peter, Yi Young Joo, Univ Missouri
- What technology area does this patent fall under?
- Primary CPC classification A61B17/43. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Sep 11 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).