Mixed allergen compositions and methods for using the same

Patent metadata

Field	Value
Publication number	US-10064936-B2
Application number	US-201615048609-A
Country	US
Kind code	B2
Filing date	Feb 19, 2016
Priority date	Feb 20, 2015
Publication date	Sep 4, 2018
Grant date	Sep 4, 2018

Abstract

Mixed allergen compositions of two or more different allergens are provided. In some instances, the mixed allergen compositions include: a nut allergen; an animal allergen; and at least one of: a non-nut plant allergen; a biotic agent; and a vitamin. Also provided are methods of administering the mixed allergen compositions to a subject. The mixed allergen compositions find use in a variety of applications, including health maintenance, immune balance, gut balance, immune support, health improvement and therapeutic applications.

First claim

That which is claimed is:

1. A mixed allergen composition comprising:
a nut allergen selected from the group consisting of a peanut allergen, an almond allergen, a walnut allergen, a cashew allergen, a hazelnut allergen, a pecan allergen and a pistachio allergen;
an animal allergen selected from the group consisting of a shrimp allergen, a cod allergen, and a salmon allergen; and
at least one of:
a non-nut plant allergen;
a biotic agent; and
a vitamin,

wherein the composition comprises equal parts by weight of the nut allergen, the animal allergen, and the non-nut plant allergen, if present.

2. The mixed allergen composition of claim 1 , wherein the composition comprises the non-nut plant allergen.

3. The mixed allergen composition of claim 1 , wherein the composition comprises the biotic agent.

4. The mixed allergen composition of claim 3 , wherein the biotic agent comprises a probiotic.

5. The mixed allergen composition of claim 3 , wherein the biotic agent comprises a prebiotic.

6. The mixed allergen composition of claim 1 , wherein the composition comprises the vitamin.

7. The mixed allergen composition of claim 1 , wherein the composition comprises the non-nut plant allergen, and the vitamin.

8. The mixed allergen composition of claim 1 , wherein the amount of each allergen present in the composition ranges from 15 to 99.9 wt. %.

9. The mixed allergen composition of claim 1 , wherein the composition further comprises
a physiologically acceptable delivery vehicle.

10. The mixed allergen composition of claim 9 , wherein the physiologically acceptable delivery vehicle is an ingestible delivery vehicle.

11. The mixed allergen composition of claim 9 , wherein the physiologically acceptable delivery vehicle is a topical delivery vehicle.

12. The mixed allergen composition of claim 9 , wherein the physiologically acceptable delivery vehicle is an injectable delivery vehicle.

13. A method of treating an allergy in a human subject in need thereof, the method comprising administering the mixed allergen composition of claim 1 to the subject.

14. The method of claim 13 , wherein the subject is a juvenile.

15. The method of claim 13 , wherein the subject is an adult.

16. The method of claim 15 , wherein the subject is pregnant with a fetus or suckling an infant.

17. The mixed allergen composition of claim 1 , wherein the non-nut plant allergen is selected from the group consisting of a wheat allergen, a sesame allergen, and an oat allergen.

18. The mixed allergen composition of claim 1 , wherein the composition further comprises an animal allergen selected from the group consisting of a chicken egg allergen, a cow milk allergen, and a crab allergen.

19. The mixed allergen composition of claim 1 , wherein the mixed allergen composition further comprises a soy allergen.

20. The mixed allergen composition of claim 1 , wherein the vitamin is selected from the group consisting of vitamin D and vitamin C.

21. The mixed allergen composition of claim 20 , wherein the vitamin is vitamin D.

22. The method of claim 13 , wherein the allergy is a food allergy.

23. The method of claim 22 , wherein the allergy is a single food allergy.

24. The method of claim 22 , wherein the allergy is a multiple food allergy.

Assignees

• Univ Leland Stanford Junior

Inventors

• Nadeau Kari C

Classifications

• A61P37/02

  Immunomodulators · CPC title

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

• A61P37/08

  Antiallergic agents (antiasthmatic agents A61P11/06; ophthalmic antiallergics A61P27/14) · CPC title

• A61P29/00

  Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title

• A61P1/00

  Drugs for disorders of the alimentary tract or the digestive system · CPC title