Methods and compositions for reducing the environmental impact of animal waste

Patent metadata

Field	Value
Publication number	US-10029002-B2
Application number	US-201615142745-A
Country	US
Kind code	B2
Filing date	Apr 29, 2016
Priority date	Feb 16, 2012
Publication date	Jul 24, 2018
Grant date	Jul 24, 2018

Abstract

Methods for reducing the environmental impact of animal waste are described. In particular embodiments, the methods comprise administering to an animal an enzyme, such as alkaline phosphatase, that is effective to reduce the amount of a detrimental compound, such as ammonia or phosphorous, that is present in or released from animal waste. Also provided is a method for increasing phosphorus digestion in an animal. Compositions suitable for use in such methods are also described.

First claim

We claim:

1. A method for reducing the environmental impact of animal waste, comprising orally administering to an animal a composition comprising an effective amount of an alkaline phosphatase comprising amino acids 33 to 572 of SEQ ID NO:1, wherein said alkaline phosphatase comprises serine at position 102 and reduces the amount of one or more detrimental compounds present in or released from animal waste, and one or more orally acceptable carriers, thereby reducing the environmental impact of animal waste.

2. The method of claim 1 , wherein said detrimental compound is ammonia or phosphorous.

3. The method of claim 1 , wherein said animal is a young animal.

4. The method of claim 1 , wherein said animal is a chicken, a turkey, a swine, or a cow.

5. The method of claim 1 , wherein the alkaline phosphatase is administered during one or more of the starter phase, the grower phase, and/or the finisher phase.

6. The method of claim 1 , wherein the alkaline phosphatase is formulated in an animal feed or an animal feed additive.

7. The method of claim 1 , wherein one or more additional active Ingredients are administered to said animal.

8. A composition suitable for oral administration to an animal comprising: an effective amount of an alkaline phosphatase comprising amino acids 33 to 572 of SEQ ID NO:1, wherein said alkaline phosphatase comprises serine at position 102 and reduces the amount of one or more detrimental compounds present in or released from animal waste, and one or more orally acceptable carriers.

9. The composition of claim 8 , wherein said detrimental compound is ammonia or phosphorous.

10. The composition of claim 8 , wherein said animal is a young animal.

11. The composition of claim 8 , wherein said animal is a chicken, a turkey, a swine, or a cow.

12. The composition of claim 8 , wherein said alkaline phosphatase is formulated to be orally administered during one or more of the starter phase, the grower phase, and/or the finisher phase.

13. The composition of claim 8 , wherein said alkaline phosphatase is formulated in an animal feed or in an animal feed additive.

14. The composition of claim 8 , wherein said composition comprises one or more additional active ingredients.

15. A method for increasing phosphorus digestion in an animal, comprising orally administering to said animal a composition comprising an effective amount of an alkaline phosphatase comprising amino acids 33 to 572 of SEQ ID NO: 1, wherein said alkaline phosphatase comprises serine at position 102, and reduces the amount of phosphorus present in or released from animal waste, and one or more orally acceptable carriers, thereby increasing digestion of phosphorus by said animal.

16. The method of claim 15 , wherein said animal is a young animal.

17. The method of claim 15 , wherein said animal is a chicken, a turkey, a swine, or a cow.

18. The method of claim 15 , wherein said alkaline phosphatase is administered during one or more of the starter phase, the grower phase, and/or the finisher phase.

19. The method of claim 15 , wherein said alkaline phosphatase is formulated in an animal feed or in an animal feed additive.

20. A method for reducing the amount of one or more detrimental compounds present in or released from animal waste, increasing animal feed conversion rate, increasing animal feed efficiency, and/or increasing animal growth rate, comprising orally administering to an animal an effective amount of a composition of claim 8 .

21. An alkaline phosphatase comprising amino acids 33 to 572 of SEQ ID NO:1, wherein said alkaline phosphatase comprises serine at position 102 and reduces the amount of one or more detrimental compounds present in or released from animal waste when administered orally to an animal.

22. The alkaline phosphatase of claim 21 , wherein said detrimental compound is ammonia or phosphorous.

Assignees

• Elanco Us Inc

Inventors

• Anderson David M
• Podkovyrov Sergey
• Huang Yuefang
• Schuster Kurt
• Ferrel Jon Edward

Classifications

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

• A61P3/00

  Drugs for disorders of the metabolism (of the blood or the extracellular fluid A61P7/00) · CPC title

• A23K50/00

  Feeding-stuffs specially adapted for particular animals · CPC title

• A23K50/30

  for swines · CPC title

• A23V2002/00

  Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title